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Encyclopedia > Distal convoluted tubule
Distal convoluted tubule
Kidney nephron (labeled as "2nd convoluted tubule", near top)
Section of cortex of human kidney.
Latin tubulus contortus distalis
Gray's subject #253 1223
Precursor Metanephric blastema
MeSH Distal+Kidney+Tubule
Dorlands/Elsevier t_22/12830066

The distal convoluted tubule (DCT) is a portion of kidney nephron between the loop of Henle and the collecting duct system. A nephron of the kidney. ... Image File history File links No higher resolution available. ... Latin is an ancient Indo-European language originally spoken in Latium, the region immediately surrounding Rome. ... This article or section is in need of attention from an expert on the subject. ... The Metanephric blastema (or metanephric mesenchyme) is one of the two embryological structures that give rise to the kidney (the other is the ureteric bud. ... Medical Subject Headings (MeSH) is a huge controlled vocabulary (or metadata system) for the purpose of indexing journal articles and books in the life sciences. ... Elseviers logo. ... It has been suggested that Renal anomalies and Renal plasma threshold be merged into this article or section. ... A nephron is the basic structural and functional unit of the kidney. ... In the kidney, the loop of Henle is the portion of the nephron that leads from the proximal convoluted tubule to the distal convoluted tubule. ... The collecting duct system of the kidney consists of: The connecting tubule The cortical collecting duct The medullary collecting duct Categories: | ...

Contents

Physiology

It is partly responsible for the regulation of potassium, sodium, calcium, and pH. General Name, Symbol, Number potassium, K, 19 Chemical series alkali metals Group, Period, Block 1, 4, s Appearance silvery white Standard atomic weight 39. ... General Name, Symbol, Number sodium, Na, 11 Chemical series alkali metals Group, Period, Block 1, 3, s Appearance silvery white Standard atomic weight 22. ... General Name, Symbol, Number calcium, Ca, 20 Chemical series alkaline earth metals Group, Period, Block 2, 4, s Appearance silvery white Standard atomic weight 40. ... The correct title of this article is . ...

  • Sodium and potassium levels are controlled by secreting K+ and absorbing Na+. Sodium absorption by the distal tubule is mediated by the hormone aldosterone. Aldosterone increases sodium reabsorption. Sodium and chlorine (salt) reabsorption is also mediated by a group of kinases called WNK kinases. There are 4 different WNK kinases, WNK1, WNK2, WNK3, and WNK4.

In inorganic chemistry, a bicarbonate (IUPAC-recommended nomenclature: hydrogencarbonate) is an intermediate form in the deprotonation of carbonic acid. ... In physics, the proton (Greek proton = first) is a subatomic particle with an electric charge of one positive fundamental unit (1. ... Norepinephrine A hormone (from Greek όρμή - to set in motion) is a chemical messenger from one cell (or group of cells) to another. ... Aldosterone is a steroid hormone synthesized from cholesterol by the enzyme aldosterone synthase. ... General Name, Symbol, Number calcium, Ca, 20 Chemical series alkaline earth metals Group, Period, Block 2, 4, s Appearance silvery white Standard atomic weight 40. ... Parathyroid hormone (PTH) is secreted by the parathyroid glands as a polypeptide containing 84 amino acids. ... Arginine vasopressin receptor 2 (AVPR2) is a protein that acts as receptor for arginine vasopressin. ...

Clinical significance

Thiazide diuretics inhibit Na+/Cl- reabsorption from the DCT by blocking the thiazide-sensitive Na-Cl cotransporter. Thiazides are a class of drug that promote water loss from the body ((diuretics)). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. ... A diuretic (colloquially called a water pill) is any drug or herb that elevates the rate of bodily urine excretion (diuresis). ... Thiazide-sensitive Na/Cl cotransporter (TSC1) is a symporter located on the lumen side of the distal convoluted tubule (DCT) in the kidney. ...


Histology

Histologically, cells of the DCT can be differentiated from cells of the proximal convoluted tubule: A thin section of lung tissue stained with hematoxylin and eosin. ... In the biology of the kidney, the proximal convoluted tubule is the segment of the renal tubule that drains Bowmans capsule. ...

Characteristic PCT DCT
apical brush border? usually have do not have
eosinophilicity? more less
cytoplasm? more less
have visible nuclei? less likely more likely

Apical, from the Latin apex (plural apices) meaning to be at the apex or tip, may refer to: An apical consonant, a consonant produced with the tip of the tongue Apical dominance An apical bud An apical pulse: apical pulse is your heart rate when counted with a stethoscope (steth... The introduction to this article provides insufficient context for those unfamiliar with the subject matter. ... Eosinophils are white blood cells that are responsible for combating infection by parasites in the body. ... Organelles. ... The eukaryotic cell nucleus. ...

Additional images

References

  1. ^ MedEd at Loyola mech/cases/case24/kidney.htm

A garden sign welcomes residents and visitors to Rogers Park as home of Loyola University Chicago. ...

External links


  Results from FactBites:
 
Distal convoluted tubule - Wikipedia, the free encyclopedia (223 words)
The distal convoluted tubule (DCT) is a portion of kidney nephron between the loop of Henle and the collecting duct system.
and absorbing Na Sodium absorption by the distal tubule is mediated by the hormone aldosterone.
Thiazide diuretics inhibit Na /Cl reabsorption from the DCT.
Magnesium Transport in the Renal Distal Convoluted Tubule -- Dai et al. 81 (1): 51 -- Physiological Reviews (7807 words)
are absorbed in the distal tubule (19, 92, 93, 248, 252,
that magnesium is reabsorbed in the superficial distal tubule,
tubule, loop of Henle, and distal tubule (83, 113).
  More results at FactBites »

 
 

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