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Encyclopedia > Diphenyl prolinol
Diphenyl prolinol
Systematic (IUPAC) name
diphenyl-[(2R)-pyrrolidin-2-yl]methanol
Identifiers
CAS number 22348-32-9
ATC code  ?
PubChem 7045371
Chemical data
Formula C17H19NO 
Mol. mass 253.33886 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

? IUPAC nomenclature is a system of naming chemical compounds and of describing the science of chemistry in general. ... CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences, mixtures and alloys. ... The Anatomical Therapeutic Chemical Classification System is used for the classification of drugs. ... PubChem is a database of chemical molecules. ... A chemical formula (also called molecular formula) is a concise way of expressing information about the atoms that constitute a particular chemical compound. ... General Name, Symbol, Number carbon, C, 6 Chemical series nonmetals Group, Period, Block 14, 2, p Appearance black (graphite) colorless (diamond) Standard atomic weight 12. ... General Name, Symbol, Number hydrogen, H, 1 Chemical series nonmetals Group, Period, Block 1, 1, s Appearance colorless Atomic mass 1. ... General Name, Symbol, Number nitrogen, N, 7 Chemical series nonmetals Group, Period, Block 15, 2, p Appearance colorless gas Standard atomic weight 14. ... General Name, Symbol, Number oxygen, O, 8 Chemical series nonmetals, chalcogens Group, Period, Block 16, 2, p Appearance colorless (gas) very pale blue (liquid) Standard atomic weight 15. ... The molecular mass (abbreviated MM) of a substance, formerly also called molecular weight and abbreviated as MW, is the mass of one molecule of that substance, relative to the unified atomic mass unit u (equal to 1/12 the mass of one atom of carbon-12). ... In pharmacology, bioavailability is used to describe the fraction of an administered dose of medication that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs. ... Drug metabolism is the metabolism of drugs, their biochemical modification or degradation, usually through specialized enzymatic systems. ... It has been suggested that Effective half-life be merged into this article or section. ... Excretion is the process of eliminating waste products of metabolism and other materials that are of no use. ... The pregnancy category of a pharmaceutical agent is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy. ...

Legal status
Routes  ?


Diphenyl prolinol, or (R,S)(+,-)-diphenyl-2-pyrrolidinyl-methanol, is a mild dopamine and norepinephrine reuptake inhibitor. The dextrorotary (R,+) enantiomer is the most pharmacologically active. Anecdotally, the dextrorotary enantiomer is orally active in the 25-100mg range, with a duration of 5-8 hours. The effects are said to be similar to other NDRIs, producing mild stimulation which is productive for working or studying, but with relatively little euphoria. Similar drugs to diphenylprolinol include pipradrol, desoxypipradrol, and to a lesser extent methylphenidate. The regulation of therapeutic goods, that is drugs and therapeutic devices, varies by jurisdiction. ... In pharmacology and toxicology, a route of administration is the path by which a drug, fluid, poison or other substance is brought into contact with the body 1. ... A Norepinephrine-dopamine reuptake inhibitor is a class of drugs that is both: Dopamine reuptake inhibitor Norepinephrine reuptake inhibitor An example is Bupropion. ... Pipradrol (Meretran) is a mild CNS stimulant which is no longer widely used in most countries due to concerns about its abuse potential, although this is less of a problem than with other stimulants that still are in current use such as methylphenidate. ... Desoxypipradrol, also known as 2-(diphenylmethyl)piperidine or 2-DPMP, is a long-acting stimulant drug. ... Methylphenidate (MPH) is an amphetamine-like prescription stimulant commonly used to treat Attention-deficit hyperactivity disorder (ADHD) in children and adults. ...


CAS numbers: 22348-32-9 or 112068-01-6 CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences and alloys. ...


External links

  • Synthesis of diphenyl-2-pyrrolidinyl-methanol and diphenyl-2-pyrrolidinyl-methane

 
 

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