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Encyclopedia > Diphenoxylate

On opiod agonist used for the treatment of diarrhea. Opium is a narcotic drug which is obtained from the unripe seed pods of the opium poppy . ... Diarrhea in American English, (spelled diarrhoea elsewhere) is a condition in which the sufferer has frequent and watery bowel movements (from the ancient Greek word διαρροή = leakage; lit. ...


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Diphenoxylate - Wikipedia, the free encyclopedia (169 words)
Diphenoxylate is an opioid agonist used for the treatment of diarrhea that acts by slowing down intestinal contractions.
Because of this, diphenoxylate is manufactured and marketed as a combination drug with atropine (LomotilĀ®).
This medication is classifed as a Schedule V under the Controlled Substances Act by the Food and Drug Administration (FDA) and the DEA in the United States when used in preparations.
Data Sheet (1295 words)
Approximately 10% of a dose of diphenoxylate is excreted in the urine and 40% in the faeces.
Diphenoxylic acid is also eliminated from plasma in a biphasic manner, and is excreted principally in urine.
DIASTOP is contraindicated in patients with known hypersensitivity to diphenoxylate hydrochloride or atropine, and in patients with jaundice.
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