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Encyclopedia > Dihydroheroin

Diacetyldihydromorphine (Paralaudin, Dihydroheroin) is a potent opiate derivative developed in Germany in 1929 which is rarely used in some countries for the treatment of strong pain such as that caused by terminal cancer, as a more potent form of diamorphine. Heroin or diamorphine (INN) (colloquially referred to as junk, babania, horse, golden brown, smack, black tar, big H, lady H, dope, skag, juice, diesel, etc. ...


Diacetyldihydromorphine is both fast acting, and also more potent and longer lasting than diamorphine (heroin), with a duration of action of around 4-7 hours. [1] These properties however make it relatively dangerous with a considerable risk of overdose or life threatening respiratory depression, and when opioids of this strength are required it is more common to use better known drugs such as oxymorphone or fentanyl which doctors will be more familiar with. Side effects are similar to those of other opiates and include itching, nausea and respiratory depression. A drug overdose occurs when a chemical substance (i. ... In medicine, hypoventilation exists when ventilation is inadequate to perform gas exchange. ... Oxymorphone (Numorphan) is a powerful semi-synthetic narcotic analgesic that is derived from morphine, and is approximately 6-8 times more potent. ... To meet Wikipedias quality standards, this article or section may require cleanup. ... An itch (Latin: pruritus) is a sensation felt on an area of skin that makes a person or animal want to scratch it. ... For other uses, see Nausea (disambiguation). ... In medicine, hypoventilation exists when ventilation is inadequate to perform gas exchange. ...


Image:Dihydroheroin.png


3,6-diacetyl-7,8-dihydromorphine


CAS# 509-71-7


References

  1. ^ Gilbert AK, Hosztafi S, Mahurter L, Pasternak GW. Pharmacological characterization of dihydromorphine, 6-acetyldihydromorphine and dihydroheroin analgesia and their differentiation from morphine. European Journal of Pharmacology 2004 May 25;492(2-3):123-30.

 
 

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