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Encyclopedia > Diffuse parenchymal lung disease
Diffuse parenchymal lung disease
ICD-10 code: J684, J701, J841, P278
ICD-9 code: 506.4, 508.1, 515, 516.3, 714.81, 770.7

Diffuse parenchymal lung disease (DPLD), also known as interstitial lung disease, refers to a group of lung diseases, affecting the alveolar epithelium, pulmonary capillary endothelium, basement membrane, perivascular and perilymphatic tissues. The term DPLD is used to distinguish these diseases from obstructive airways diseases. Most types of DPLD involve fibrosis, but this is not essential; indeed fibrosis is often a later feature. Hence the term pulmonary fibrosis has fallen out of favor. The following codes are used with International Statistical Classification of Diseases and Related Health Problems. ... // J00-J99 - Diseases of the respiratory system (J00-J06) Acute upper respiratory infections (J00) Acute nasopharyngitis (common cold) (J01) Acute sinusitis (J02) Acute pharyngitis (J03) Acute tonsillitis (J04) Acute laryngitis and tracheitis (J05) Acute obstructive laryngitis (croup) and epiglottitis (J050) Acute obstructive laryngitis (croup) (J051) Acute epiglottitis (J06) Acute upper... // J00-J99 - Diseases of the respiratory system (J00-J06) Acute upper respiratory infections (J00) Acute nasopharyngitis (common cold) (J01) Acute sinusitis (J02) Acute pharyngitis (J03) Acute tonsillitis (J04) Acute laryngitis and tracheitis (J05) Acute obstructive laryngitis (croup) and epiglottitis (J050) Acute obstructive laryngitis (croup) (J051) Acute epiglottitis (J06) Acute upper... // J00-J99 - Diseases of the respiratory system (J00-J06) Acute upper respiratory infections (J00) Acute nasopharyngitis (common cold) (J01) Acute sinusitis (J02) Acute pharyngitis (J03) Acute tonsillitis (J04) Acute laryngitis and tracheitis (J05) Acute obstructive laryngitis (croup) and epiglottitis (J050) Acute obstructive laryngitis (croup) (J051) Acute epiglottitis (J06) Acute upper... // P00-P96 - Certain conditions originating in the perinatal period (P00-P04) Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery (P00) Fetus and newborn affected by maternal conditions that may be unrelated to present pregnancy (P01) Fetus and newborn affected by maternal complications of... The following is a list of codes for International Statistical Classification of Diseases and Related Health Problems. ... The parenchyma are the functional parts of an organ in the body (i. ... The lungs flank the heart and great vessels in the chest cavity. ... Detailed drawing of the alveoli from Grays Anatomy, 1918 - Schematic longitudinal section of a primary lobule of the lung (anatomical unit); r. ... In zootomy, epithelium is a tissue composed of a layer of cells. ... Capillaries are the smallest of a bodys blood vessels, measuring 5-10 μm. ... The endothelium is the layer of thin, flat cells that lines the interior surface of blood vessels, forming an interface between circulating blood in the lumen and the rest of the vessel wall. ... Fibrosis is the formation or development of excess fibrous connective tissue in an organ or tissue as a reparative or reactive process, as opposed to formation of fibrous tissue as a normal constituent of an organ or tissue. ...

Contents


Causes

DPLD may be classified according to the cause: -

  1. Inhaled substances
  2. Drug induced
  3. Connective tissue disease
  4. Infection
  5. Idiopathic
    • Sarcoidosis
    • Idiopathic pulmonary fibrosis
    • Hamman-Rich syndrome
  6. Malignancy

Inorganic chemistry is the branch of chemistry concerned with the properties and reactions of inorganic compounds. ... The chemical compound silicon dioxide, also known as silica, is the oxide of silicon, chemical formula SiO2. ... Fibrous asbestos on muscovite Asbestos Asbestos Asbestos (a misapplication of Latin: asbestos quicklime from Greek ἄσβεστος: a-, not; sbestos, extinguishable) describes any of a group of fibrous metamorphic minerals of the hydrous magnesium silicate variety. ... General Name, Symbol, Number beryllium, Be, 4 Chemical series alkaline earth metals Group, Period, Block 2, 2, s Appearance white-gray metallic Atomic mass 9. ... For other uses, see Life (disambiguation) and Living (disambiguation). ... Hypersensitivity pneumonitis is an inflammation of the lung caused by the bodys immune reaction to small air-borne particles. ... Look up drug in Wiktionary, the free dictionary. ... An antibiotic is a drug that kills or slows the growth of bacteria. ... Chemotherapy is the use of chemical substances to treat disease. ... Antiarrhythmic agents are a group of pharmaceuticals that are used to suppress fast rhythms of the heart (cardiac arrhythmias), such as atrial fibrillation, atrial flutter, ventricular tachycardia, and ventricular fibrillation. ... X-Ray of the knee in a patient with dermatomyositis. ... Rheumatoid arthritis (RA) is a chronic, inflammatory autoimmune disorder that causes the immune system to attack the joints. ... An infection is the detrimental colonization of a host organism by a foreign species. ... Pneumonia is an illness of the lungs and respiratory system in which the microscopic, air-filled sacs (alveoli) responsible for absorbing oxygen from the atmosphere become inflamed and flooded with fluid. ... Pneumocystis carinii pneumonia (PCP) is a form of pneumonia which is caused by a microorganism called Pneumocystis carinii (It has been proposed that the organism be renamed Pneumocystis jiroveci). ... Tuberculosis is an infection with the bacterium Mycobacterium tuberculosis, which most commonly affects the lungs (pulmonary TB) but can also affect the central nervous system (meningitis), lymphatic system, circulatory system (miliary TB), genitourinary system, bones and joints. ... Idiopathic is a medical adjective that indicates that a recognized cause has not yet been established. ... Hamman-Rich syndrome (also known as acute interstitial pneumonia) is a rare, severe lung disease which usually affects otherwise healthy individuals. ... When normal cells are damaged or old they undergo apoptosis; cancer cells, however, avoid apoptosis. ... In medicine, carcinoma is any cancer that arises from epithelial cells. ...

Investigation

Investigation is tailored towards the symptoms and signs. Most patients have blood testing, chest x-ray, pulmonary function testing, and high resolution CT thorax. In the NATO phonetic alphabet, X-ray represents the letter X. An X-ray picture (radiograph) taken by Röntgen An X-ray is a form of electromagnetic radiation with a wavelength approximately in the range of 5 pm to 10 nanometers (corresponding to frequencies in the range 30 PHz... CAT apparatus in a hospital Computed axial tomography (CAT), computer-assisted tomography, computed tomography, CT, or body section roentgenography is the process of using digital processing to generate a three-dimensional image of the internals of an object from a large series of two-dimensional X-ray images taken around...


Treatment

DPLD is not a single disease, but encompasses many different pathological processes. Hence treatment is different for each disease.


If a specific occupational exposure cause is found, the person should avoid that environment. If a drug cause is suspected, that drug should be discontinued.


Many idiopathic and connective tissue-based causes of DPLD are treated with prednisolone. Some patients respond to immunosuppressant treatment. Patients with hypoxemia may be given supplemental oxygen. Prednisolone is a synthetic corticosteroid drug which is usually taken orally and can be used for a large number of different conditions. ... Immunosuppression is the medical suppression of the immune system. ... Hypoxemia or reduced oxygen in the blood, can be caused by: 1. ... General Name, Symbol, Number oxygen, O, 8 Chemical series Chalcogens Group, Period, Block 16, 2, p Appearance colorless Atomic mass 15. ...


External links


  Results from FactBites:
 
Diffuse Interstitial Lung Disease - Health Centers (699 words)
Diffuse interstitial pulmonary fibrosis is the name given to a group of disorders characterized by inflammation and eventually scarring of the deep lung tissues, leading to shortness of breath.
Interstitial lung diseases (ILD) are a group of diseases caused by inflammation and scarring of the alveoli (air sacs) and their supporting structures (the interstitium).
Exposure to agents known to cause lung disease (certain dusts, gases, fumes, vapors, medications, and radiation) should be restricted.
Postgraduate Medicine: Occupational lung disease (3091 words)
This form of silica-related lung disease is known as complicated silicosis (figure 2).
Hypersensitivity pneumonitis is a diffuse lung disease caused by organic respiratory inhalant exposures.
Diffuse parenchymal lung disease (also known as interstitial lung disease) and acute irritant reactions are much less commonly managed by primary care physicians than asthma.
  More results at FactBites »

 
 

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