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Encyclopedia > Cytidine

Cytidine is a molecule (known as a nucleoside) that is formed when cytosine is attached to a ribose ring (also known as a ribofuranose) via a β-N1-glycosidic bond.



If cytosine is attached to a deoxyribose ring, it is known as a deoxycytidine.


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BioMed Central | Full text | Maize haplotype with a helitron-amplified cytidine deaminase gene copy (6341 words)
Cytidine deaminases are a superfamily, which includes Cytidine deaminase, nucleoside deaminase, deoxycytidylate deaminase and riboflavin deaminase.
They are enzymes that de-aminate cytidine to uridine and play an important role in a variety of pathways from bacteria to man. Ancestral members of this superfamily were only able to de-aminate cytidine of mononucleotides or nucleosides.
The cytidine deaminase super-family can be classified into RNA-editing deaminases, cytidine deaminases, nucleoside deaminases and deoxycytidylate deaminases, based on substrate specificity and homology of the active-site sequence [26].
Olympus MIC-D: Polarized Light Gallery - Cytidine (325 words)
Cytosine, the organic base of cytidine, was first isolated from the thymus of a calf in 1894 and was synthesized in the laboratory in 1903.
As a crystal, cytidine appears as a white or almost white powder and is available in a chemically synthesized regular or radiolabeled form.
The enzyme is used by geneticists and gene therapists for cutting and splicing DNA and RNA segments, and may explain somatic mutations and evolution by viral and bacterial vectors.
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