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Encyclopedia > Cushing ulcer

A Cushing ulcer is a gastric ulcer produced by elevated intracranial pressure. It is also called as von Rokitansky-Cushing syndrome. Apart from in the stomach, it may also develop in the proximal part of the duodenum and the distal esophagus. Intracranial pressure, (ICP), is the pressure exerted by the cranium on the brain tissue, cerebrospinal fluid (CSF), and the brains circulating blood volume. ... Carl Freiherr von Rokitansky (Czech: Karel Rokytanský) (b. ... Harvey Cushing (c. ... In anatomy, the stomach is a bean-shaped hollow muscular organ of the gastrointestinal tract involved in the second phase of digestion, following mastication. ...

One possible explanation for the development of Cushing ulcers is the stimulation of vagal nuclei due to the increased intracranial pressure which leads to increasd secretion of gastric acid.

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Harvey Williams Cushing (www.whonamedit.com) (6034 words)
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An ulcer (from Latin ulcus) is an open sore of the skin, eyes or mucous membrane, often caused by an initial abrasion and generally maintained by an inflammation and/or an infection.
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