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Encyclopedia > Coniine
Image is drawn in bkchem and GIMP. This image has been released into the public domain by the copyright holder, its copyright has expired, or it is ineligible for copyright. ... chemical structure of coniine

Coniine or 2-propylpiperidine is a poisonous alkaloid found in Binomial name Conium maculatum L. Conium is a genus of 2-3 species of perennial herbaceous plants in the family Apiaceae. ...poison hemlock. It is a A neurotoxin is a toxin that acts specifically on nerve cells, or neurons, usually by interacting with membrane proteins and ion channels. ...neurotoxin which disrupts the central nervous system. It is toxic to all classes of livestock and humans. Socrates Scholasticus; for the Brazilian football player, see Sócrates (football player) Socrates Socrates (June 4, 470 – 399 BC) (Greek Σωκράτης Sōkrátēs) was a Greek (Athenian) philosopher and one of the most important icons of the Western philosophical tradition. ...Socrates was put to death by way of this poison in 399 B.C.

Its chemical formula is General Name, Symbol, Number Carbon, C, 6 Chemical series Nonmetals Group, Period, Block 14 (IVA), 2, p Density, Hardness 2267 kg/m3 0. ...C8 General Name, Symbol, Number Hydrogen, H, 1 Chemical series nonmetals Group, Period, Block 1 (IA), 1 , s Density, Hardness 0. ...H17 General Name, Symbol, Number Nitrogen, N, 7 Chemical series nonmetals Group, Period, Block 15 (VA), 2 , p Density 1. ...N.


Coniine was the first of the alkaloids ever synthesised by Albert Ladenburg (* September 3, 1842; † August 15, 1911) was a german Chemist. ...Albert Ladenburg in 1886 is a common year starting on Friday (click on link to calendar) Events January 18 _ Modern field hockey is born with the formation of The Hockey Association in England. ...1886.


coniin synthese File links The following pages link to this file: Coniine ...

The original synthesis of this Categories: Chemistry stubs ...piperidine by Ladenburg started by heating methylpyridinium iodide at 300°C (not shown)to obtain 2_methyl pyridine. 2_methyl pyridine (alpha_Picoline) reacts with Acetaldehyde, also known as ethanal, is a chemical compound, an aldehyde with formula CH3CHO and structure It is a highly reactive flammable liquid with a strong fruity smell. ...Acetaldehyde in presence of a The common (Arrhenius) definition of a base is a chemical compound that either donates hydroxide ions or absorbs hydrogen ions when dissolved in water. ...base to 2_Propenyl Pyridine is a clear liquid with a strong and very unpleasant odor that is used as a solvent and reagent in organic chemistry. ...pyridine in a The Knoevenagel condensation reaction is a organic reaction named after Emil Knoevenagel. ...Knoevenagel condensation. This intermediate was A reducing agent is a substance used in electrochemistry that reduces another substance. ...reduced with metallic General Name, Symbol, Number sodium, Na, 11 Series alkali metal Group, Period, Block 1 (IA), 3 , s Density, Hardness 968 kg/m3, 0. ...sodium in Ethyl alcohol, also known as ethanol or grain alcohol, is a flammable, colorless chemical compound, one of the alcohols that is most often found in alcoholic beverages. ...ethanol to In chemistry, a racemate is a mixture of equal amounts of left_ and right_handed stereoisomers of a chiral molecules. ...racemic (+_) Coniine (reduction by hydrogen gas is also possible). In chemistry two stereoisomers are said to be enantiomers if one can be superimposed on the mirror image of the other. ...Enantiopure Coniine was obtained by fractional Crystal (disambiguation) Insulin crystals A crystal is a solid in which the constituent atoms, molecules, or ions are packed in a regularly ordered, repeating pattern extending in all three spatial dimensions. ...crystallisation of the Diastereomers are stereoisomers that are not enantiomers or mirror images of each other. ...diastereoisomers of the salt obtained with (+)_ Tartaric acid is white crystalline organic acid. ...tartaric acid.

External links

  • http://www.chm.bris.ac.uk [1]  (http://www.chm.bris.ac.uk/motm/hemlock/intro.htm)

  Results from FactBites:
Coniine - Wikipedia, the free encyclopedia (204 words)
Coniine was the first of the alkaloids ever synthesised (by Albert Ladenburg in 1886).
This intermediate was reduced with metallic sodium in ethanol to racemic (+-) Coniine (reduction by hydrogen gas is also possible).
Enantiopure Coniine was obtained by fractional crystallisation of the diastereoisomers of the salt obtained with (+)-tartaric acid.
structure.html (575 words)
Coniine's LD50 in mice is 100 mg/Kg (oral) with death in 10 minutes.
Coniine had been studied a little because it was commercially available, and it was known that its actions resembled that of nicotine, a pyridine alkaloid in both the CNS and PNS.
Paralysis by the hemlock alkaloids is caused at the neuromuscular junction.
  More results at FactBites »



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