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Encyclopedia > Chymotrypsinogen

Chymotrypsinogen is a precursor of the digestive enzyme chymotrypsin (zymogen).


This molecule is inactive and must be cleaved by trypsin, and then by other chymotrypsin molecules before it can reach its full activity.


  Results from FactBites:
 
AllRefer.com - chymotrypsin (Biochemistry) - Encyclopedia (194 words)
Chymotrypsin is produced in the pancreas as the inactive, or zymogen, form chymotrypsinogen.
Along with other digestive enzymes of the pancreas, chymotrypsinogen is carried in the pancreatic juice through the pancreatic duct into the duodenum.
There chymotrypsinogen is activated by another enzyme, trypsin, and by molecules of active chymotrypsin.
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