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Encyclopedia > Chromosome 3 (human)

Chromosome 3 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 3 spans almost 200 million base pairs (the building material of DNA) and represents about 6.5 percent of the total DNA in cells. Image File history File links Chromosome_3. ... Figure 1: Chromosome. ... Trinomial name Homo sapiens sapiens Linnaeus, 1758 Humans, or human beings, are bipedal primates belonging to the mammalian species Homo sapiens (Latin for wise man or knowing man) under the family Hominidae (known as the great apes). ... In molecular biology, two nucleotides on opposite complementary DNA or RNA strands that are connected via hydrogen bonds are called a base pair (often abbreviated bp). ... The general structure of a section of DNA Deoxyribonucleic acid (DNA) is a nucleic acid that contains the genetic instructions for the biological development of a cellular form of life or a virus. ... Cells in culture, stained for keratin (red) and DNA (green). ...


Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 3 likely contains between 1,100 and 1,500 genes. This stylistic schematic diagram shows a gene in relation to the double helix structure of DNA and to a chromosome (right). ...

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Genes

The following are some of the genes located on chromosome 3:

  • ALAS1: aminolevulinate, delta-, synthase 1
  • BTD: biotinidase
  • CCR5: chemokine (C-C motif) receptor 5
  • CPOX: coproporphyrinogen oxidase (coproporphyria, harderoporphyria)
  • HGD: homogentisate 1,2-dioxygenase (homogentisate oxidase)
  • MCCC1: methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)
  • MITF: microphthalmia-associated transcription factor
  • MLH1: mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
  • PCCB: propionyl Coenzyme A carboxylase, beta polypeptide
  • PDCD10: programmed cell death 10
  • PIK3CA: phosphoinositide-3-kinase, catalytic, alpha polypeptide
  • RAB7: RAB7, member RAS oncogene family
  • SCN5A: sodium channel, voltage-gated, type V, alpha (long QT syndrome 3)
  • SLC25A20: solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
  • TMIE: transmembrane inner ear
  • USH3A: Usher syndrome 3A
  • VHL: von Hippel-Lindau tumor suppressor
  • ZNF9: zinc finger protein 9 (a cellular retroviral nucleic acid binding protein)
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BTD (biotinidase) is a human gene that provides instructions for making an enzyme called biotinidase. ... CCR5, short for chemokine (C-C motif) receptor 5, is a chemokine receptor. ... SCN5A is a sodium ion channel associated with long QT syndrome type 3 (LQT3), Brugada syndrome, and idiopathic ventricular fibrillation. ... Von Hippel-Lindau disease (VHL) is a rare inherited genetic condition involving the abnormal growth of tumors in parts of the body which are particularly rich in blood supply. ...

Diseases

The following diseases are some of those related to genes on chromosome 3:

Human chromosomes

{1} {2} {3} {4} {5} {6} {7} {8} {9} {10} {11} {12} {13} {14} {15} {16} {17} {18} {19} {20} {21} {22} {X} {Y} Alkaptonuria also known as alcaptonuria or ochronosis is a rare inherited genetic disorder of tyrosine metabolism. ... Biotin, also known as vitamin H or B7 and C10H16N2O3S (Biotin; Coenzyme R, Biopeiderm), is a water-soluble B-complex vitamin which is composed of an ureido ring fused with a tetrahydrothiophene ring. ... The Brugada syndrome is a genetic disease that is manifest by abnormal electrocardiogram (ECG) findings and an increased risk of sudden cardiac death. ... Carnitine-acylcarnitine translocase deficiency is a rare condition that prevents the body from converting long-chain fatty acids into energy, particularly during periods without food. ... The foot of a person with Charcot-Marie-Tooth. ... To meet Wikipedias quality standards, this article may require cleanup. ... The porphyrias are inherited or acquired disorders of certain enzymes in the heme biosynthetic pathway (also called porphyrin pathway). ... Hereditary nonpolypsis colorectal cancer (HNPCC) is characterized by an increased risk of colon cancer and other cancers such as endometrium, ovary, stomach, small intestine, hepatobiliary tract, upper urinary tract, brain, and skin. ... 3-methylcrotonyl-CoA carboxylase deficiency is an inherited disorder in which the body is unable to process certain proteins properly. ... To meet Wikipedias quality standards, this article may require cleanup. ... Nonsyndromic deafness is hearing loss that is not associated with other signs and symptoms. ... This article is about the disease. ... Propionic acidemia is an inherited disorder of inborn error of intermediary metabolism that may present in the early neonatal period with progressive encephalopathy. ... Romano-Ward syndrome, is the major variant of long QT syndrome. ... Usher syndrome is a genetic disease causing deaf-blindness. ... Von Hippel-Lindau disease (VHL) is a rare inherited genetic condition involving the abnormal growth of tumors in parts of the body which are particularly rich in blood supply. ... Waardenburg syndrome is an inherited disorder associated with hearing loss and changes in skin and hair pigmentation. ... Autism is classified as a neurodevelopmental disorder that manifests itself in markedly abnormal social interaction, communication ability, patterns of interests, and patterns of behavior. ... Nyctalopia (literally night blindness) is a condition making it difficult or impossible to see in the dark. ... An editor has expressed a concern that the topic of this article may be unencyclopedic. ... This article is about the disease that features high blood sugar. ... Ovarian cancer is a malignant ovarian neoplasm (an abnormal growth located on the ovaries). ... People who are shorter have short stature. ... Spinocerebellar ataxia (SCA) is a genetic disease with multiple types, each of which could be considered a disease in its own right. ... Moyamoya disease is an extremely rare disorder in most parts of the world except in Japan. ... The long QT syndrome (LQTS) is a heart disease in which there is an abnormally long delay between the electrical excitation (or depolarization) and relaxation (repolarization) of the ventricles of the heart. ... Cataract is also used to mean a waterfall or where the flow of a river changes dramatically. ... The mucopolysaccharidoses are inborn errors of metabolism resulting from the deficiency of specific lysosomal enzymes needed in glycosaminoglycan catabolism. ... Cerebral cavernous malformations (CCM), also known as cavernous angioma, cavernous haemangioma, and cavernoma, is a vascular disorder of the central nervous system that may appear either sporadically or exhibit autosomal dominant inheritance. ... Protein S deficiency is a disorder associated with increased risk of thrombosis. ... The porphyrias are inherited or acquired disorders of certain enzymes in the heme biosynthetic pathway (also called porphyrin pathway). ... The dopamine receptors are a class of metabotropic G-protein-coupled receptors with the neurotransmitter dopamine as their endogenous ligand. ... Glycogen storage disease is any one of several inborn errors of metabolism that result from enzyme defects that affect the processing of glycogen synthesis or breakdown within muscles, liver, and other cell types. ... Arrhythmogenic right ventricular dysplasia (ARVD, also known as arrhythmogenic right ventricular cardiomyopathy or ARVC) is a type of nonischemic cardiomyopathy that involves primarily the right ventricle. ... Lymphoma is a general term for cancers that develop in the lymphatic system. ... Clinical features Mobius syndrome(Moebius is an alternate spelling, the two can be used interchangeably)is caused by an abnormal neurodevelopment of the cranial nerves. ... The human genome is the genome of Homo sapiens. ... Chromosome 1 is, by convention, the designation for the largest human chromosome. ... Chromosome 2 is one of the 23 pairs of chromosomes in humans. ... Chromosome 4 is one of the 23 pairs of chromosomes in humans. ... Chromosome 5 is one of the 23 pairs of chromosomes in humans. ... Chromosome 6 is one of the 23 pairs of chromosomes in humans. ... Chromosome 7 is one of the 23 pairs of chromosomes in humans. ... Chromosome 8 is one of the 23 pairs of chromosomes in humans. ... Chromosome 9 is one of the 23 pairs of chromosomes in humans. ... Chromosome 10 is one of the 23 pairs of chromosomes in humans. ... Chromosome 11 is one of the 23 pairs of chromosomes in humans. ... Chromosome 12 is one of the 23 pairs of chromosomes in humans. ... Chromosome 13 is one of the 23 pairs of chromosomes in humans. ... Chromosome 14 is one of the 23 pairs of chromosomes in humans. ... Chromosome 15 is one of the 23 pairs of chromosomes in humans. ... Chromosome 16 is one of the 23 pairs of chromosomes in humans. ... Chromosome 17 is one of the 23 pairs of chromosomes in humans. ... Chromosome 18 is one of the 23 pairs of chromosomes in humans. ... Chromosome 19 is one of the 23 pairs of chromosomes in humans. ... Chromosome 20 is one of the 23 pairs of chromosomes in humans. ... A common disease due to 3 of such chromosomes instead of the normal 2 is called Down syndrome. ... Chromosome 22 is one of the 23 pairs of chromosomes in humans. ... The X chromosome is one of the two sex chromosomes in mammals (the other is the Y chromosome). ... The human Y chromosome is one of two sex chromosomes, it contains the genes that cause testis development, thus determining maleness. ...


  Results from FactBites:
 
The Human Genome (first draft) - Chromosome 3 (195 words)
COLON CANCER- MLH1 on chromosome 3 and MSH2 on chromosome 2.
ESSENTIAL TREMOR- In 1997, the ETM1 gene (also called FET1) was mapped to chromosome 3 in a study of Icelandic families.
NCBI Genes and Diseases Chromosome 1 - 4
Chromosome 3 - Genetics Home Reference (387 words)
Chromosome 3 is one of the 23 pairs of chromosomes in humans.
Chromosome 3 spans almost 200 million base pairs (the building material of DNA) and represents about 6.5 percent of the total DNA in cells.
Genes on chromosome 3 are among the estimated 20,000 to 25,000 total genes in the human genome.
  More results at FactBites »

 
 

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