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Encyclopedia > Christian Boehmer Anfinsen

Christian Boehmer Anfinsen, Jr. (March 26, 1916 _ May 14, 1995) was a chemist and a 1972 Nobel Prize winner for work on ribonuclease, especially concerning the connection between the amino acid sequence and the biologically active conformation.

Anfinsen was born in Monessen, Pennsylvania. He earned a bachelor's degree from Swarthmore College in 1937, a master's degree in organic chemistry from the University of Pennsylvania in 1939, and a Ph.D. in 1939 from Harvard University.

In 1961 he showed that ribonuclease could be refolded after denaturation while preserving enzyme activity, thereby suggesting that all the information required by protein to adopt its final conformation is encoded in its primary structure.

He was a convert to Judaism by going through the gijur_process.

  Results from FactBites:
NIH News Release--Papers of Nobel Scientist Christian Anfinsen Added to "Profiles In Science" Web Site- - 11/02/2000 (878 words)
Christian Anfinsen (1916-1995) is the fifth scientist to be added to NLM's "Profiles in Science" website (http://www.profiles.nlm.nih.gov) "Profiles in Science is now becoming a major online resource on which to store the public and private-and sometimes intimate-papers of this century's greatest biomedical scientists" says Dr. Donald Lindberg, director of the National Library of Medicine.
Anfinsen, a biochemist at the National Institutes of Health from 1950 until 1981, was awarded the 1972 Nobel Prize in Chemistry for his work on the structure and composition of proteins in living cells.
Christian Boehmer Anfinsen, Jr., was born to Norwegian immigrants on March 26, 1916 in Monessen, Pennsylvania, a small town south of Pittsburgh.
Christian Boehmer Anfinsen Biography (1017 words)
Biochemist Christian Boehmer Anfinsen is known for establishing that the structure of an enzyme is intimately related to its function.
Anfinsen began his research concerning the structure and function of enzymes in the mid-1940s.
Anfinsen was a member of the National Academy of Sciences, the American Society of Biological Chemists, and the Royal Danish Academy.
  More results at FactBites »



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