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Encyclopedia > Carcinoma in situ

Carcinoma in situ is present when a tumor has been detected that has the characteristics of malignancy but has not invaded other tissues. Many forms of cancer are initially carcinomas in situ, but are not detected early enough.

Many clinicians would not refer to carcinoma in situ as "cancer" when relating results to a patient. Conversely, although many are treated much the same way as a proven malignancy, there may be important differences in the therapeutical management.

Examples of carcinomas in situ are: -

  • Many bladder cancers are CISes.
  • Cervical cancer is often predated by cervical intraepithelial neoplasia (CIN).
  • Similarly, vaginal tumors are VaIN (vaginal intraepithelial neoplasia) when they are still at in situ stage; vulval tumors begin as VIN (vulval intraepithelial neoplasia).

  Results from FactBites:
Carcinoma in situ definition - Cancer information on MedicineNet.com (199 words)
Carcinoma in situ: Cancer that involves only the place in which it began and that has not spread.
For example, squamous cell carcinoma in situ (Bowen's disease) is an early cancer of the skin.
The term "in situ" (borrowed from the Romans) means "in the natural or normal place" and, in the case of cancer, it means that the tumor cells are still confined to the site where they originated and they have neither invaded neighboring tissues nor metastasized afar.
Discovery Health :: Diseases & Conditions :: carcinoma in situ (463 words)
Carcinoma in situ of the breast may be found when a small change is noted on a mammogram.
Carcinoma in situ of the bladder may be found when the internal wall of the bladder is examined for other reasons.
Carcinoma in situ is diagnosed by taking a sample, called a biopsy, of the area.
  More results at FactBites »



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