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Encyclopedia > Calcidiol
Calcidiol
Systematic name (6R)-6-[(1R,3aR,4E,7aR)-4-[(2Z)-2-[(5S)-5-Hydroxy-2-methylidene-cyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]-2-methyl-heptan-2-ol
Other names 25-Hydroxyvitamin D3
25-Hydroxycholecalciferol
Calcifediol
Identifiers
CAS number [19356-17-3]
PubChem 5283731
MeSH Calcidiol
SMILES C[C@H](CCCC(C)(C)O)[C@H]1CC[C@@H]2[C@@]1(CCC/C2=CC=C/3C[C@H](CCC3=C)O)C
Properties
Molecular formula C27H44O2
Molar mass 400.637
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Calcidiol, calcifediol, 25-hydroxycholecalciferol, or 25–hydroxy–vitamin D, is a prehormone which is produced by the metabolism of vitamin D3 (cholecalciferol) and which is converted by the kidneys into calcitriol (1,25-vitamin D), a steroid hormone. IUPAC nomenclature is a system of naming chemical compounds and of describing the science of chemistry in general. ... CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences, mixtures and alloys. ... PubChem is a database of chemical molecules. ... Medical Subject Headings (MeSH) is a huge controlled vocabulary (or metadata system) for the purpose of indexing journal articles and books in the life sciences. ... The simplified molecular input line entry specification or SMILES is a specification for unambiguously describing the structure of chemical molecules using short ASCII strings. ... A chemical formula (also called molecular formula) is a concise way of expressing information about the atoms that constitute a particular chemical compound. ... Molar mass is the mass of one mole of a chemical element or chemical compound. ... In chemistry, the standard state of a material is its state at 1 bar (100 kilopascals) and 25 degrees Celsius (298. ... Overview of the citric acid cycle The citric acid cycle, one of the central metabolic pathways in aerobic organisms. ... Chemical structure of cholecalciferol Cholecalciferol is a form of Vitamin D. Vitamin D3 is also a steroid much like testosterone, cholesterol and cortisol. ... Vitamin D is a fat soluble vitamin that contributes to the maintenance of normal levels of calcium and phosphorus in the bloodstream. ... Steroid skeleton of lanosterol. ... Norepinephrine A hormone (from Greek όρμή - to set in motion) is a chemical messenger from one cell (or group of cells) to another. ...


Clinical significance

In medicine, bloodstream concentration of calcidiol is commonly used to measure overall vitamin D levels. Calcifediol promotes the mineralization of bones and teeth and is used to treat diseases caused by vitamin D deficiency such as rickets and osteomalacia. It is effective even in azotemic patients.[citation needed] Mineralization is the process of depositing minerals or naturally occuring inorganic chemicals. ... It has been suggested that Osteomalacia be merged into this article or section. ... To meet Wikipedias quality standards, this article may require cleanup. ...


References

  • Dietary Reference intakes for Calcium, Phosphorus, Magnesium, Vitamin D and Fluoride. Institute of Medicine, 1997
  • Vitamin D Pharmacology at VitaminDCouncil.com

 
 

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