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Encyclopedia > Bufotenine
Bufotenin
Formula C12H16N2O
Molecular mass 204.27 g/mol
SMILES CN(C)CCC1=CNC2=C1C=C(O)C=C2
The chemical structure of bufotenin


Bufotenin, also spelled bufotenine, is also known under the names 5_hydroxy_DMT (5-OH-DMT) or dimethyl-serotonin and is a tryptamine related to the neurotransmitter serotonin. It is an alkaloid found in many plants that has originally been isolated from the gland secretes of toads, most notably Bufo alvarius, from where it derives the name Bufotenin. Bufotenin is a hallucinogenic compound.

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Pharmacology of Bufotenine (0 words)
In spite of bufotenine's Schedule I status in the United States, no laws were violated, neither technically nor de facto, in the course of this research - evidently only in the U.S. is bufotenine illicit; all chemical and psychonautic work was conducted in countries in which bufotenine is not a controlled substance.
For inhaled-vapor tests, bufotenine was weighed on a square of heavy-gauge aluminum foil subsequently fashioned as a ball, into the opening of which the flared end of a female ball-jointed glass tube would just fit.
Stromberg, V.L. The isolation of bufotenine from Piptadenia peregrina.
Heavyweights.ca Message Board - near death experiences (3013 words)
Bufotenine and N,N-dimethyltryptamine (DMT) are hallucinogenic dimethylated indolethylamines (DMIAs) formed from serotonin and tryptamine by the enzyme indolethylamine N-methyltransferase (INMT) ubiquitously present in non-neural tissues.
Endogenous levels of bufotenine and DMT in blood and a number of animal and human tissues were determined using highly sensitive and specific quantitative mass spectrometric techniques.
It is suggested that fecal and urinary bufotenine originate from epithelial cells of the intestine and the kidney, respectively, although the possibility of their synthesis by intestinal bacteria cannot be excluded.
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