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Encyclopedia > Brazilian purpuric fever

Brazilian purpuric fever (BPF) is a fulminant sceptacaemic illness of children caused by the gram negative bacteria Haemophilus influenzae biogroup aegyptius Binomial name Haemophilus influenzae Lehmann & Neumann, 1896 Haemophilus influenzae, formerly called Pfeiffers bacillus, is a non-motile Gram-negative coccobacillus first described in 1892 by Dr. Robert Pfeiffer during the influenza pandemic. ... Haemophilus influenzae biogroup aegyptius (Hae) was discovered independently by Koch and Weeks in the 1880s. ...

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Dorlands Medical Dictionary (3859 words)
fever associated with aseptic wounds, presumably due to the disintegration of leukocytes or to the absorption of avascular or traumatized but uninfected tissue.
Symptoms include fever of insidious onset, headache, dry cough, back pain, vomiting, diarrhea, pharyngitis, facial edema, and occasionally a maculopapular rash; in severe cases there is a sudden drop in blood pressure on the seventh day, with death resulting from shock, hypotension, peripheral vasoconstriction, hypovolemia, and anuria.
a hemorrhagic fever similar in its clinical manifestations to Kyasanur Forest disease, endemic in a forested region of western Siberia, and caused by a flavivirus, transmitted to humans by the bites of infected ticks of the genus Dermacentor or by direct contact with infected muskrats, as by fur trappers.
Morbidity and Mortality Weekly Report: Brazilian purpuric fever - Mato Grosso, Brazil (984 words)
Brazilian purpuric fever (BPF) is a life-threatening pediatric infection that is preceded by conjunctivitis and caused by a specific strain of Haemophilus influenzae biogroup aeygptius (BPF clone) (*) [1-4].
BPF was recognized during 1984 in the state of Sao Paulo, Brazil, when 10 children in a town of 20,000 persons died of an acute febrile illness associated with purpura and vascular collapse [5,6].
During the epidemiologic investigation of BPF in Mato Grosso, a randomized study was conducted to compare the efficacy of topical chloramphenicol with that of oral rifampin for conjunctival eradication of the BPF clone among children with BPF clone conjunctivitis.
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