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Encyclopedia > Bolivian hemorrhagic fever
Bolivian hemorrhagic fever
Classification & external resources
ICD-10 A96.1
ICD-9 078.7
?
Machupo virus
Virus classification
Group: Group V ((-)ssRNA)
Family: Arenaviridae
Genus: Arenavirus
Species

Machupo virus
The International Statistical Classification of Diseases and Related Health Problems (most commonly known by the abbreviation ICD) provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or disease. ... The following codes are used with International Statistical Classification of Diseases and Related Health Problems. ... The International Statistical Classification of Diseases and Related Health Problems (most commonly known by the abbreviation ICD) provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or disease. ... The following is a list of codes for International Statistical Classification of Diseases and Related Health Problems. ... Virus classification involves naming and placing viruses into a taxonomic system. ... An RNA virus is a virus that either uses RNA as its genetic material, or whose genetic material passes through an RNA intermediate during replication. ... Arenavirus is a genus of virus. ... Arenavirus is a genus of virus. ...

Bolivian hemorrhagic fever (BHF), also known as black typhus or Machupo virus, is a hemorrhagic fever and zoonotic infectious disease occurring in Bolivia. First identified in 1959, black typhus is caused by infection with machupo virus, a negative single-stranded RNA virus of the Arenaviridae family. The infection has a slow onset with fever, malaise, headache and muscular pains. Petechiae (blood spots) on the upper body and bleeding from the nose and gums are observed when the disease progresses to the hemorrhagic phase, usually within seven days of onset. The mortality rate is estimated at 5 to 30 percent. Due to its pathogenicity, Machupo virus requires Biosafety Level Four conditions, the highest level. Viral hemorrhagic fevers are a group of illnesses that are caused by several distinct families of viruses: Arenavirus, Filoviridae, Bunyaviridae and Flavivirus. ... Zoonosis (pronounced as zoo-on-no-sis) is any infectious disease that may be transmitted from animals, both wild and domestic, to humans. ... This false-colored electron micrograph shows a malaria sporozoite migrating through the midgut epithelia. ... This article or section does not adequately cite its references or sources. ... Arenavirus is a genus of virus. ... An infection is the detrimental colonization of a host organism by a foreign species. ... An analogue medical thermometer showing the temperature of 38. ... Malaise is a term used to refer to a general state of discomfort, tiredness, or illness. ... A headache is a condition of pain in the head; sometimes neck or upper back pain may also be interpreted as a headache. ... minor Petechia A petechia (IPA pronunciation: ), plural petechiae (IPA pronunciation: ) is a small red or purple spot on the body, caused by a minor hemorrhage (broken capillary blood vessels). ... For the article about nose in humans, see human nose Human nose in profile Elephants have prehensile noses Dogs have very sensitive noses Anatomically, a nose is a protuberance in vertebrates that houses the nostrils, or nares, which admit and expel air for respiration. ... To meet Wikipedias quality standards, this article or section may require cleanup. ... Pathogenicity is the ability of an organism to cause disease in another organism. ... The U.S. Centers for Disease Control and Prevention (CDC) specifies four levels of biocontainment precautions for biological agents, Biosafety Levels 1 through 4. ...


The vector is the vesper mouse (Calomys callosus), a rodent indigenous to northern Bolivia. Infected animals are asymptomatic and shed virus in excretions, by which humans are infected. Evidence of person-to-person transmission of Machupo virus exists but is believed to be rare (Kilgore, et. al, 1995). Traditionally in medicine, a vector is an organism that does not cause disease itself but which spreads infection by conveying pathogens from one host to another. ... Species Calomys boliviae Calomys callidus Calomys callosus Calomys hummelincki Calomys laucha Calomys lepidus Calomys musculinus Calomys sorellus Calomys tener Calomys tocantinsi Calomys is a genus of rodents, also called Vesper mice. ... Suborders Sciuromorpha Castorimorpha Myomorpha Anomaluromorpha Hystricomorpha Rodentia is an order of mammals also known as rodents. ...


Measures to reduce contact between the vesper mouse and humans have effectively limited the number of outbreaks, with no cases identified between 1973 and 1994. A vaccine being developed for the genetically related Junín virus which causes Argentine hemorrhagic fever has shown evidence of cross-reactivity with Machupo virus and may be an effective prophylactic measure for people at high risk of infection. Species Junín virus Argentine hemorrhagic fever, known locally as mal de los rastrojos, is a hemorrhagic fever and zoonotic infectious disease occurring in Argentina. ... This page is a candidate to be moved to Wiktionary. ...


There are no cures or immunisations for this disease, although those who have contracted it are immune. Treatment options are limited, mostly to supportive care, but are sometimes successful if started early.


References

  • Kilgore, Paul E., et al. "Prospects for control of Bolivian Hemorrhagic Fever." >Emerging Infectious Diseases: 1 (3).

  Results from FactBites:
 
Bolivian hemorrhagic fever (230 words)
Bolivian hemorrhagic fever (BHF), also known as fl typhus or Machupo virus, is a hemorrhagic fever and zoonotic infectious disease occurring in Bolivia.
Petechiae (blood spots) on the upper body and bleeding from the nose and gums are observed when the disease progresses to the hemorrhagic phase, usually within seven days of onset.
A vaccine being developed for the genetically related Junin virus which causes Argentine hemorrhagic fever has shown evidence of cross-reactivity with Machupo virus and may be an effective prophylactic measure for people at high risk of infection.
hemorrhagic fever: Definition and Much More from Answers.com (2547 words)
Crimean-Congo hemorrhagic fever is caused by nairovirus and occurs in central and southern Africa, Asia, Eurasia, and the Middle East.
Hemorrhagic fever with renal (kidney) syndrome is caused by the hantaviruses: Hantaan, Seoul, Puumala, and Dobrava.
Since the hemorrhagic fevers share symptoms with many other diseases, positive identification of the disease relies on evidence of the viruses in the bloodstream—such as detection of antigens and antibodies—or isolation of the virus from the body.
  More results at FactBites »

 
 

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