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Encyclopedia > Benzylmorphine
Systematic (IUPAC) name
CAS number 14297-87-1
ATC code  ?
PubChem 5362507
Chemical data
Formula C24H25NO3 
Mol. mass 375.46 g/mol
Synonyms Benzylmorphine, Peronine
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

? Shortcut: WP:-( Vandalism is indisputable bad-faith addition, deletion, or change to content, made in a deliberate attempt to compromise the integrity of the encyclopedia. ... Shortcut: WP:-( Vandalism is indisputable bad-faith addition, deletion, or change to content, made in a deliberate attempt to compromise the integrity of the encyclopedia. ... IUPAC nomenclature is a system of naming chemical compounds and of describing the science of chemistry in general. ... CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences, mixtures and alloys. ... The Anatomical Therapeutic Chemical Classification System is used for the classification of drugs. ... PubChem is a database of chemical molecules. ... This article does not cite its references or sources. ... General Name, Symbol, Number carbon, C, 6 Chemical series nonmetals Group, Period, Block 14, 2, p Appearance black (graphite) colorless (diamond) Standard atomic weight 12. ... General Name, Symbol, Number hydrogen, H, 1 Chemical series nonmetals Group, Period, Block 1, 1, s Appearance colorless Atomic mass 1. ... General Name, Symbol, Number nitrogen, N, 7 Chemical series nonmetals Group, Period, Block 15, 2, p Appearance colorless gas Standard atomic weight 14. ... General Name, Symbol, Number oxygen, O, 8 Chemical series nonmetals, chalcogens Group, Period, Block 16, 2, p Appearance colorless (gas) very pale blue (liquid) Standard atomic weight 15. ... The molecular mass (abbreviated MM) of a substance, formerly also called molecular weight and abbreviated as MW, is the mass of one molecule of that substance, relative to the unified atomic mass unit u (equal to 1/12 the mass of one atom of carbon-12). ... Synonyms can be nouns, adverbs or adjectives, as long as both members of the pair are the same part of speech. ... In pharmacology, bioavailability is used to describe the fraction of an administered dose of unchanged drug that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs. ... Drug metabolism is the metabolism of drugs, their biochemical modification or degradation, usually through specialized enzymatic systems. ... It has been suggested that Effective half-life be merged into this article or section. ... Excretion is the process of eliminating waste products of metabolism and other materials that are of no use. ... The pregnancy category of a pharmaceutical agent is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy. ...

Legal status

Schedule I(US) The regulation of therapeutic goods, that is drugs and therapeutic devices, varies by jurisdiction. ... The Controlled Substances Act (CSA) was enacted into law by the Congress of the United States as Title II of the Comprehensive Drug Abuse Prevention and Control Act of 1970. ... Motto: (Out Of Many, One) (traditional) In God We Trust (1956 to date) Anthem: The Star-Spangled Banner Capital Washington D.C. Largest city New York City None at federal level (English de facto) Government Federal constitutional republic  - President George Walker Bush (R)  - Vice President Dick Cheney (R) Independence from...

Routes  ?

Benzylmorphine (Peronine®) is a semi-synthetic opiate narcotic invented in 1897. In pharmacology and toxicology, a route of administration is the path by which a drug, fluid, poison or other substance is brought into contact with the body 1. ... Semisynthesis or partial chemical synthesis uses compounds isolated from natural sources (e. ... Look up narcotic in Wiktionary, the free dictionary. ...

Benzylmorphine is used in much the same way as codeine and dihydrocodeine, primarily as a moderate strength analgesic and cough suppressant. It was available in the United States prior to 1914 and was still used until the 1960s, but fell into disuse once alternative opiate derivatives became more preferred by doctors (i.e. hydrocodone as an analgesic and pholcodeine as a cough suppressant) Benzylmorphine is now a Schedule I Controlled Substance in the USA and is regulated internationally under UN drug conventions. [1] Codeine (INN) or methylmorphine is an opiate used for its analgesic, antitussive and antidiarrheal properties. ... Dihydrocodeine, also called DHC and Paracodeine and by the brand names of SS Bron, Drocode, Paracodin, Codidol, Didor Continus, Dicogesic, and DF-118 amongst others, is a semi-synthetic opioid analgesic prescribed for postoperative pain, severe dyspnea, or as an antitussive. ... This article or section does not adequately cite its references or sources. ... It has been suggested that Vicodin be merged into this article or section. ... Pholcodeine is an opioid used primarily as an antitussant (to treat cough) with little abuse potential. ... The Controlled Substances Act (CSA), Title II of the Comprehensive Drug Abuse Prevention and Control Act of 1970, is the legal foundation of the United States governments fight against the abuse of drugs and other substances. ...


  1. ^ Single Convention On Narcotic Drugs 1961 (United Nations)
  • Merck Manual, 1900
  • Merck Index, 1998
  • United States Department of Justice, Drug Enforcement Administration: Controlled Substances in Schedule I

  Results from FactBites:
UNODC - Bulletin on Narcotics - 1955 Issue 2 - 005 (748 words)
The Committee noted further that the evidence accompanying the notification regarding dihydrohydroxymorphinone indicated particularly dangerous addiction-producing properties of this substance and was of the opinion that other less dangerous drugs offer equal therapeutic advantage and emphasized the desirability of avoiding the manufacture, import and export of dihydrohydroxymorphinone.
Referring to the notification of the Government of the United State of America, the Committee was of the opinion that there was no evidence that the myristyl ester of benzylmorphine process addiction liability.
However, it had information that it can be readily convertible to benzylmorphine or morphine in yields of at least 50 to 60 %.
UNODC - Bulletin on Narcotics - 1951 Issue 2 - 005 (7221 words)
Codeine may be regarded as the first of a series of phenolic ethers of morphine, the most important of which are ethylmorphine or dionine, and benzylmorphine or peronine.
Dionine is sometimes used in ophthalmology because of its power to produce irritation and hyperaemia of the eye, desirable in certain cases.
Benzylmorphine or peronine is a more active but also a more toxic substitute for codeine.
  More results at FactBites »



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