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Encyclopedia > Benzonatate
Benzonatate
Systematic (IUPAC) name
2-[2-[2-[2-[2-[2-[2-[2- (2-methoxyethoxy) ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethyl4-butylaminobenzoate
Identifiers
CAS number 104-31-4
ATC code R05DB01
PubChem 7699
DrugBank APRD00629
Chemical data
Formula C30H53NO11 
Mol. mass 603.742 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life 3- 8 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.

? Image File history File links No higher resolution available. ... IUPAC nomenclature is a system of naming chemical compounds and of describing the science of chemistry in general. ... CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences, mixtures and alloys. ... The Anatomical Therapeutic Chemical Classification System is used for the classification of drugs. ... A section of the Anatomical Therapeutic Chemical Classification System. ... PubChem is a database of chemical molecules. ... The DrugBank database available at the University of Alberta is a unique bioinformatics and cheminformatics resource that combines detailed drug (i. ... A chemical formula (also called molecular formula) is a concise way of expressing information about the atoms that constitute a particular chemical compound. ... General Name, Symbol, Number carbon, C, 6 Chemical series nonmetals Group, Period, Block 14, 2, p Appearance black (graphite) colorless (diamond) Atomic mass 12. ... General Name, Symbol, Number hydrogen, H, 1 Chemical series nonmetals Group, Period, Block 1, 1, s Appearance colorless Atomic mass 1. ... General Name, Symbol, Number nitrogen, N, 7 Chemical series nonmetals Group, Period, Block 15, 2, p Appearance colorless gas Atomic mass 14. ... General Name, Symbol, Number oxygen, O, 8 Chemical series nonmetals, chalcogens Group, Period, Block 16, 2, p Appearance colorless (gas) very pale blue (liquid) Atomic mass 15. ... The molecular mass (abbreviated MM) of a substance, formerly also called molecular weight and abbreviated as MW, is the mass of one molecule of that substance, relative to the unified atomic mass unit u (equal to 1/12 the mass of one atom of carbon-12). ... In pharmacology, bioavailability is used to describe the fraction of an administered dose of medication that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs. ... Drug metabolism is the metabolism of drugs, their biochemical modification or degradation, usually through specialized enzymatic systems. ... It has been suggested that Effective half-life be merged into this article or section. ... Excretion is the process of eliminating waste products of metabolism and other materials that are of no use. ... The pregnancy category of a pharmaceutical agent is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy. ...

Legal status
Routes  ?

Benzonatate or 2,5,8,11,14,17,20,23,26-nonaoxaoctacosan-28-yl para-butylaminobenzoate is a non-narcotic oral antitussive (cough suppressant) drug which works by anesthetizing the tissues of the lungs and pleura responsible for the cough reflex. It is chemically related to other ester anesthetics such as procaine. According to the Medicine.net article, it has an anesthetic (numbing) action similar to that of benzocaine and "numbs" the stretch sensors in the lungs, and it is the stretching of these sensors with breathing that causes the cough. It's not related to opioids or dextromethorphan. Brand name Tessalon Perles. The regulation of therapeutic goods, that is drugs and therapeutic devices, varies by jurisdiction. ... In pharmacology and toxicology, a route of administration is the path by which a drug, fluid, poison or other substance is brought into contact with the body 1. ... Look up narcotic in Wiktionary, the free dictionary. ... A cough medicine is a drug used to treat coughing and related conditions. ... Anesthesia or anaesthesia (see spelling differences) has traditionally meant the condition of having the perception of pain and other sensations blocked. ... The heart and lungs (from an older edition of Grays Anatomy) The lung is an organ belonging to the respiratory system and interfacing to the circulatory system of air-breathing vertebrates. ... In anatomy, the pleural cavity is the potential space between the lungs and the chest wall. ... A reflex action or reflex is a biological control system linking stimulus to response and mediated by a reflex arc. ... General formula of a carboxylate ester. ... For other uses of the name Novocaine and other spellings thereof, see Novocaine (disambiguation). ... Benzocaine is a local anesthetic commonly used as a topical pain reliever. ... An opioid is any agent that binds to opioid receptors found principally in the central nervous system and gastrointestinal tract. ... Dextromethorphan (DM or DXM) is an antitussive drug that is found in many over-the-counter cold and cough preparations, usually in the form of dextromethorphan hydrobromide. ...


External sources

  • MedLinePlus Government Information about how to take the drug
  • Medicine.net article describing how it works.

  Results from FactBites:
 
MedlinePlus Drug Information: Benzonatate (613 words)
Benzonatate is used to treat cough due to the common cold, bronchitis, pneumonia, or other lung infections.
Benzonatate is in a class of medications called antitussives (cough suppressants).
Benzonatate comes as a liquid-filled capsule (perle) and a regular capsule to take by mouth.
  More results at FactBites »

 
 

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