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Encyclopedia > Basal optic nucleus of Meynert
Brain: Basal optic nucleus of Meynert
Latin n. basalis telencephali
NeuroNames hier-257
MeSH Basal+nucleus+of+Meynert
Dorlands/Elsevier n_11/12580484

In the lateral part of the tuber cinereum is a nucleus of nerve cells, the basal optic nucleus of Meynert. Latin is an ancient Indo-European language originally spoken in Latium, the region immediately surrounding Rome. ... NeuroNames is a system of nomenclature for the brain and related structures. ... Medical Subject Headings (MeSH) is a huge controlled vocabulary (or metadata system) for the purpose of indexing journal articles and books in the life sciences. ... Elseviers logo. ... The tuber cinereum is a hollow madda of gray substance situated between the corpora mammillaria behind, and the optic chiasma in front. ...


The basal nucleus of Meynert (NBM) is a group of nerve cells in the substantia innominata that has wide projections to the neocortex and is rich in acetylcholine and choline acetyltransferase. In Parkinson and Alzheimer diseases the nucleus undergoes degeneration. A decrease in acetylcholine production is seen in Alzheimer's disease, Lewy body dementia and some Parkinson Disease patients showing abnormal brain function, leading to a general decrease of mental capacity and learning. Most pharmacological treatments of dementia focus on compensating for a faltering NBM function through artificially increasing acetylcholine levels.


The primary concentration of cholinergic neurons/cell bodies that project to the neocortex are in the basal nucleus of Meynert which is located in the substantia innominata of the anterior perforated substance.


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This article was originally based on an entry from a public domain edition of Gray's Anatomy. As such, some of the information contained herein may be outdated. Please edit the article if this is the case, and feel free to remove this notice when it is no longer relevant. The public domain comprises the body of all creative works and other knowledge—writing, artwork, music, science, inventions, and others—in which no person or organization has any proprietary interest. ... An illustration from the 1918 edition Henry Grays Anatomy of the Human Body, commonly known as Grays Anatomy after Henry Gray, is an anatomy textbook widely regarded as a classic work on human anatomy. ...


 
 

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