The human body makes hundreds of different types of B cells, and each type has a unique receptor protein on its membrane that will bind to one particular antigen; at any one time in the human body millions of B cells are circulating in the blood and lymph, but are not producing antibodies. There are two types of B cells:
Memory B cells are formed specific to the antigen(s) encountered during the primary immune response; able to live for a long time, these cells can respond quickly upon second exposure to the antigen for which they are specific.
Humoral immunity (the creation of antibodies that circulate in blood plasma and lymph) involves B cell activation. Cell activation can be gauged using the ELISPOT technique, which can determine the percentage of B cells that secrete any particular antibody.
B cells are characterised immunohistochemically by the presence of CD20 on the cell membrane.
T cells are named such because these lymphocytes mature in the thymus; Bcells, named for the bursa of Fabricius in which they mature in bird species, are thought to mature in the bone marrow in humans.
A lymphocyte count is part of a peripheral complete bloodcell count and is expressed as percentage of lymphocytes to total white bloodcells counted.
Share your thoughts, questions and commentary here
Want to know more? Search encyclopedia, statistics and forums:
Press Releases |
The Wikipedia article included on this page is licensed under the
Images may be subject to relevant owners' copyright.
All other elements are (c) copyright NationMaster.com 2003-5. All Rights Reserved.
Usage implies agreement with terms, 1022, m