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Encyclopedia > Antipyretic

Antipyretics are drugs that prevent or reduce fever by lowering the body temperature from a raised state. However, they will not affect the normal body temperature if one does not have fever. Oral medication A medication is a licenced drug taken to cure or reduce symptoms of an illness or medical condition. ... See Fever for the Kylie Minogue album; Fever is also a song by Otis Blackwell. ...


Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever. In the anatomy of mammals, the hypothalamus is a region of the brain located below the thalamus, forming the major portion of the ventral region of the diencephalon and functioning to regulate certain metabolic processes and other autonomic activities. ... Interleukins are a group of cytokines that are expressed by white blood cells (leukocytes, hence the -leukin) as a means of communication (inter-). The function of the immune system depends in a large part on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune...


Most are also used for other purposes. For example, the most common antipyretics in the United States are aspirin and acetaminophen, which are used primarily as pain relievers. There is some debate over the appropriate use of such medications: fever is part of the body's immune response to infection. Aspirin or acetylsalicylic acid is a drug in the family of salicylates, often used as an analgesic (against minor pains and aches), antipyretic (against fever), and anti-inflammatory. ... Acetaminophen (USAN) or paracetamol (INN), is a popular analgesic and antipyretic drug that is used for the relief of fever, headaches, and other minor aches and pains. ... Pain is an unpleasant sensation which may be associated with actual or potential tissue damage and which may have physical and emotional components. ... The immune system is the system of specialized cells and organs that protect an organism from outside biological influences. ...


Herbal remedies with a fever-reducing effect are called febrifuges, and include catnip, chamomile, sage and yarrow. However, the term "febrifuge" can also refer to a refrigerant, such as topical alcohol, which cools the body by physically removing heat rather than modifying the body's responses. The term Herbalism refers to folk and traditional medicinal practice based on the use of plants and plant extracts. ... It has been suggested that this article or section be merged with Nepeta. ... Chamomile flowers The name Chamomile or Camomile is ambiguous and can refer to several distinct species. ... Binomial name Salvia officinalis L. Common sage (Salvia officinalis) is a small evergreen subshrub, with woody stems, grayish leaves, and blue to purplish flowers native to southern Europe and the Mediterranean region. ... Binomial name Achillea millefolium L. Yarrow (Achillea millefolium) is a common herb found throughout North America and Eurasia. ... A refrigerant is a compound used in a heat cycle that undergoes a phase change from a gas to a liquid and back. ... Ethanol, also known as ethyl alcohol or grain alcohol, is a flammable, colorless chemical compound, one of the alcohols that is most often found in alcoholic beverages. ...


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BioMed Central | Full text | Alternating ibuprofen and acetaminophen in the treatment of febrile children: a pilot ... (3735 words)
However, combined antipyretic treatment can be dangerous and may precipitate hepatic or renal toxicities due to glutathione pathway impairment, especially in the sick, dehydrated or fasting child [6-8,10-14].
This antipyretic effect was maintained for an additional two hours in the intervention group, as evidenced by the significantly higher proportions of afebrile subjects at 7 and 8 hours from baseline.
In addition, the antipyretic advantage of the combined antipyretics may be attenuated with multiple dosing of ibuprofen and acetaminophen, and become comparable to repeated ibuprofen mono-therapy.
Antipyretic, Analgesic and Anti-Inflammatory Effects of Delta-9-Tetrahydrocannabinol in the Rat (1170 words)
The comparative oral antinociceptive activity of delta-9-THC and selected narcotic and non-narcotic analgesics was determined by the increase in response latency to pressure applied to normal and yeast-inflamed paws.
Although the antipyretic actions of phenylbutazone are generally considered to be mediated by central mechanisms similar to those of the salicylates, no direct evidence for a central site of antipyretic action for delta-9-THC is provided in the present study.
Accordingly, the antipyretic effects produced by relatively low doses of delta-9-THC may be due in part to non-specific peripheral effects such as vasodilatation, as suggested by Beaconsfield et al.
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