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Encyclopedia > Androgen binding protein

Androgen binding protein is a protein produced by the Sertoli cells in the seminiferous tubules that binds androgen hormones like testosterone. The Sertoli cell is the nurse cell of the testes. ... Human male anatomy The testicles, known medically as testes (singular testis), are the male generative glands in animals. ...

  Results from FactBites:
Sex hormone binding globulin - Wikipedia, the free encyclopedia (265 words)
Sex hormone-binding globulin (SHBG) is a glycoprotein that binds to sex hormones, specifically testosterone and estradiol.
In addition SHBG is produced by the testis; testis-produced SHBG is also called androgen-binding protein.
Also, high androgen levels decrease SHBG, while high estrogen and thyroxine levels increase it.
Meiotic Arrest and Germ Cell Apoptosis in Androgen-Binding Protein Transgenic Mice -- Selva et al. 141 (3): 1168 -- ... (6530 words)
Apoptotic DNA fragmentation in the testis of nontransgenic littermates (lanes 1 and 3) and ABP transgenic animals (lanes 2 and 4).
that in ABP transgenic mice pachytene spermatocytes and metaphase
ABP that is responsible for the interruption of spermatogenesis.
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