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Encyclopedia > Amacrine cell

Amacrine cell Retinal cell interneuron interacting at the Inner Plexiform Layer (IPL), the second synaptic retinal layer where bipolar cells and ganglion cells synapse. Most amacrine cell types lack an axon. There are about 40 different types. Classification is based on width of field of connection, and layer(s) of stratum/i in the IPL where the cell is located as well as neurotransmitter type. Most are inhibitory using either GABA or glycine as neurotransmitters. Human eye cross-sectional view. ... An interneuron is a neuron that communicates only to other neurons. ... As a part of the retina, the bipolar cell exists between photoreceptors and ganglion cells. ... A ganglion cell (or sometimes called a gangliocyte) is a type of neuron located in the retina that receives visual information from photoreceptors via various intermediate cells such as bipolar cells, amacrine cells, and horizontal cells. ... Synapses allow nerve cells to communicate with one another through axons and dendrites, converting electrical signals into chemical ones. ... An axon, or nerve fiber, is a long slender projection of a nerve cell, or neuron, which conducts electrical impulses away from the neurons cell body or soma. ... Chemical structure of GABA Gamma-aminobutyric acid (GABA) is a neurotransmitter in widely divergent species. ... Glycine is a nonpolar amino acid. ... Neurotransmitters are chemicals that are used to relay, amplify and modulate electrical signals between two neurons: the presynaptic neuron and the postsynaptic neuron. ...


External links

Webvision amacrine cell article (http://webvision.med.utah.edu/amacrines1.html)


  Results from FactBites:
 
Webvision: Amacrine cells (1602 words)
Cell A13 is a diffusely branched cell with a large cell body (12 um diameter) and fine dendrites bearing distinct beads at regular intervals that run through mostly strata 3-5 of sublamina b of the IPL to end up along the top of ganglion cell bodies.
The cone bipolar inputs are from axons in sublamina a, stratum 3-4 of sublamina b and stratum 5 of sublamina b.
SP-containing and A22 cells are wide-field amacrine cells (dendritic trees of 500 um span), often having large cell bodies (14-16 um) displaced to the ganglion cell layer, with their major dendritic stratification in strata 3 and 4 of sublamina b of the IPL.
Dissociated Retinal Cell Scoring (1493 words)
Rods tend to be the smallest cells in the field and the rhodopsin staining is in the pattern of a uniform ring around the nucleus which tend to be perfectly round.
Amacrine cell subtypes exhibit the same morphology, are found in the same sublaminae of the INL and exhibit a regular mosaic across the retina.
Amacrine subtypes should give uniform staining from cell to cell while there may be variation in the single cell staining of amacrine subpopulations which reflects the distinct subtypes.
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