Alloimmunity is a condition in which the body gains immunity against cells from another individual of the same species. It can occur after allografts (grafts) or transfusions of fluids such as blood or plasma. In a medical sense, immunity is a state of having sufficient biological defenses to avoid infection, disease, or other unwanted biological invasion. ... Cells in culture, stained for keratin (red) and DNA (green) The cell is the structural and functional unit of all living organisms, and are sometimes called the building blocks of life. ... In horticulture, a graft is where the tissues of one plant are affixed to the tissues of another; the process is called grafting. ... Blood transfusion is the taking of blood or blood-based products from one individual and inserting them into the circulatory system of another. ... Red blood cells (erythrocytes) are present in the blood and help carry oxygen to the rest of the cells in the body Blood is a circulating tissue composed of fluid plasma and cells (red blood cells, white blood cells, platelets). ... Blood plasma is the liquid component of blood, in which the blood cells are suspended. ...
Alloimmunity should not be confused with autoimmunity. Autoimmunity details a condition in which the body attacks its own cells. Autoimmune diseases arise from an overactive immune response of the body against substances and tissues normally present in the body. ...
Alloimmunity is a condition in which the body gains immunity, from another individual of the same species, against its own cells.
Alloimmunity should not be confused with autoimmunity in which the body's immune system attacks its own cells without being provoked or influenced by substances or cells from another member of the same species.
in the fetus after maternal antibodies have passed through the placenta into the fetus, as in haemolytic disease of the newborn and fetomaternal alloimmune thrombocytopenia.
There are evidences that many auto-immune diseases and alloimmunity are characteristic of vertebrates and that they are associated with MHC molecules.
Alloimmunity can be another by-product of evolution of the adoptive immunity which emerged under selection pressure of microbes and “latently” accumulated enormous strength.
As in the case of autoimmunity, selection pressure of alloimmunity caused the emergence of fine mechanisms for the control of immune reaction on one hand and absence of expression of MHC molecules on placental tissues, on the other – except for monomorphic and low-polymorphic MHC class Ib molecules.
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