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Encyclopedia > Alfentanil

Alfentanil (Alfenta) is a parenteral short-acting opioid painkiller, used for anaesthesia in surgery. While it gives less cardiovascular complications, it tends to give stronger respiratory depression. Alfentanil is a Schedule I drug under the Single Convention on Narcotic Drugs[1]. In pharmacology and toxicology, a route of administration is the path by which a drug, fluid, poison or other substance is brought into contact with the body 1. ... An opioid is any agent that binds to opioid receptors found principally in the central nervous system and gastrointestinal tract. ... An analgesic (colloquially known as painkiller) is any member of the diverse group of drugs used to relieve pain and to achieve analgesia. ... Anesthesia (AE), also anaesthesia (BE), is the process of blocking the perception of pain and other sensations. ... A typical modern surgery operation For other meanings of the word, see Surgery (disambiguation) Surgery (from the Greek cheirourgia meaning hand work) is the medical specialty that treats diseases or injuries by operative manual and instrumental treatment. ... The circulatory system or cardiovascular system is the organ system which circulates blood around the body of most animals. ... In medicine, hypoventilation exists when ventilation is inadequate to perform gas exchange. ... Single Convention on Narcotic Drugs Opened for signature March 30, 1961 at New York Entered into force December 13, 1964[1] Conditions for entry into force 40 ratifications Parties 180[2] The Single Convention on Narcotic Drugs is the international treaty against illicit drug manufacture and trafficking that forms the...


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Analgesics edit

{Paracetamol (acetaminophen)} {NSAIDs} {Opiates} {Tetrahydrocannabinol} {Ketamine} An analgesic (colloquially known as painkiller) is any member of the diverse group of drugs used to relieve pain and to achieve analgesia. ... Paracetamol (INN) or acetaminophen (USAN) is a popular analgesic and antipyretic drug that is used for the relief of fever, headaches, and other minor aches and pains. ... Wikipedia does not yet have an article with this exact name. ... An opioid is any agent that binds to opioid receptors found principally in the central nervous system and gastrointestinal tract. ... Tetrahydrocannabinol, also known as THC, Δ9-THC, Δ9-tetrahydrocannabinol (delta-9-tetrahydrocannabinol), Δ1-tetrahydrocannabinol (using an older numbering scheme), or dronabinol. ... Ketamine is a general dissociative anaesthetic for human and veterinary use. ...

NSAIDs edit

{Acetaminophen} {Aspirin} {Celecoxib} {Diclofenac} {Ibuprofen} {Ketoprofen} {Ketorolac} {Meloxicam} {Naproxen} {Rofecoxib} {Indomethacin} Non-steroidal anti-inflammatory drugs, usually abbreviated to NSAIDs, are drugs with analgesic, antipyretic and anti-inflammatory effects - they reduce pain, fever and inflammation. ... Acetaminophen (USAN) or paracetamol (INN), is a popular analgesic and antipyretic drug that is used for the relief of fever, headaches, and other minor aches and pains. ... Aspirin or acetylsalicylic acid is a drug in the family of salicylates, often used as an analgesic (against minor pains and aches), antipyretic (against fever), and anti-inflammatory. ... Celecoxib is a non-steroidal anti-inflammatory drug (NSAID) used in the treatment of osteoarthritis, rheumatoid arthritis, acute pain, painful menstruation and menstrual symptoms, and to reduce numbers of colon and rectum growths polyps in patients with familial adenomatous polyposis. ... Diclofenac (marketed as Voltaren®, Voltarol® and Cataflam®) is a non-steroidal anti-inflammatory drug (NSAID) taken to reduce inflammation, such as in arthritis or acute injury. ... Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) widely marketed under various trademarks including Act-3, Advil, Brufen, Motrin, Nuprin, and Nurofen; a standing joke about some athletes regular use has produced Vitamin I as a slang term for it. ... Ketoprofen, 2-(3-benzoylphenyl)-propionic acid (chemical formula C12H12O2) is one of the propionic acid class of non-steroidal anti-inflammatory drug (NSAID) with additional analgesic and anti-pyretic effects. ... Ketorolac or ketorolac tromethamine (marketed as Toradol® - generics have been approved) is a non-steroidal anti-inflammatory drug (NSAID) in the family of propionic acids, often used as an analgesic, antipyretic (fever reducer), and anti-inflammatory. ... Meloxicam is a nonsteroidal anti-inflammatory drug used to relieve the symptoms of arthritis, primary dysmenorrhoea, pyrexia; and as an analgesic, especially where there is an inflammatory component. ... Naproxen (trade names: Aleve, Anaprox, Naprosyn, Naprelan) is a non-steroidal anti-inflammatory drug (NSAID) commonly used for the reduction of mild to moderate pain, fever, inflammation and stiffness caused by conditions such as osteoarthritis, rheumatoid arthritis, psoriatic arthritis, gout, ankylosing spondylitis, injury, menstrual cramps, tendinitis, bursitis, and the treatment... Rofecoxib is a nonsteroidal anti-inflammatory drug (NSAID) that was used in the treatment of osteoarthritis, acute pain conditions, and dysmenorrhoea. ... Indomethacin (also indometacin) is a non-steroidal anti-inflammatory drug commonly used to reduce fever, pain, stiffness, and swelling. ...

Opioids edit

{Alfentanil} {Buprenorphine} {Carfentanil} {Codeine} {Codeinone} {Dextropropoxyphene} {Dihydrocodeine} {Fentanyl} {Heroin} {Hydrocodone} {Hydromorphone} {Methadone} {Morphine} {Morphinone} {Oxycodone} {Oxymorphone} {Pethidine (Meperidine)} {Remifentanil} {Sufentanil} {Tramadol} An opioid is any agent that binds to opioid receptors found principally in the central nervous system and gastrointestinal tract. ... Buprenorphine, also colloquially referred to as bupe, is an opioid drug with partial agonist and antagonist actions. ... Carfentanil, also Carfentanyl, is an analogue of the popular opioid Fentanyl, and is currently the most potent opioid known [Actually Ohmefentanil is 13,000X morphine]. It has a quantitative potency approximately 10,000 times that of morphine and 100 times that of fentanyl (activity in humans starting at about 1... Codeine (INN) is an opioid used for its analgesic, antitussive and antidiarrheal properties. ... Codeinone is a strong Opiod. ... Dextropropoxyphene is an analgesic in the opioid category. ... penis ... Fentanyl is an opioid analgesic, first synthesized in Belgium in the late 1950s, with an analgesic potency of about 80 times that of morphine. ... Heroin or diacetylmorphine (INN) is an semi-synthetic opioid. ... Hydrocodone or dihydrocodeinone (marketed as Vicodin, Anexsia, Dicodid, Hycodan, Hycomine, Lorcet, Lortab, Norco, Tussionex, Vicoprofen) is an opioid derived from either of the naturally occurring opiates - codeine or thebaine. ... // Overview Hydromorphone is a drug used to relieve moderate to severe pain. ... Methadone is a synthetic opioid analgesic synthesized in 1937 by German scientists Max Bockmühl and Gustav Ehrhart at IG Farben (Hoechst-Am-Main) who were searching for an analgesic that would be easier to use during surgery and also have low addiction potential. ... Morphine (INN), the principal active agent in opium, is a powerful opioid analgesic drug. ... Morphinone is a very strong Opiod. ... Oxycodone is a very powerful and potentially addictive opioid analgesic medication synthesized from thebaine. ... Oxymorphone is a powerful synthetic narcotic analgesic drug that is similar to morphine. ... Pethidine (INN) or meperidine (USAN) (also referred to as: isonipecaine; lidol; operidine; pethanol; piridosal; Algil®; Alodan®; Centralgin®; Demerol®; Dispadol®; Dolantin®; Dolestine®; Dolosal®; Dolsin®; Mefedina®) is a fast-acting opioid analgesic drug. ... Remifentanil is a short-acting opioid analgesic drug, given to patients during surgery to relieve pain and as a complement to an anaesthetic. ... Sufentanil is a drug that belongs to the class of drugs known as the opioid analgesic drugs. ... Tramadol is an opioid used as an analgesic for treating moderate to severe pain. ...


  Results from FactBites:
 
ALFENTANIL (364 words)
Alfentanil is a synthetic derivative of fentanyl with distinct properties, e.g.
Alfentanil is metabolised in the liver by cytochrome CYP3A4 to inactive compounds.
Alfentanil is available only as an injection and has been used successfully by short-term CSCI to provide pain relief during dressing changes in a trauma patient.
vuyk (396 words)
While the target concentration of propofol was maintained constant, the target concentration of alfentanil was varied in steps of 10-50 ng/ml according to the presence or absence of patient responses to perioperative stimuli.
The alfentanil concentrations associated with a 50% probability (EC50s) of suppression of responses to intraabdominal surgical stimuli, as determined by logistic regression in the individual patients, were related to corresponding mean blood propofol concentrations by nonlinear regression analysis.
With plasma alfentanil concentrations increasing from 10 to 150 ng/ml, the EC50 of propofol for the regaining of consciousness decreased from 3.8 to 0.8 microgram/ml.
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