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Encyclopedia > Adrenergic

An adrenergic is a drug, or other substance, which has effects similar to, or the same as, epinephrine (adrenaline). Alternatively, it may refer to something which is susceptible to epinephrine, or similar substances, such as a biological receptor (specifically, the adrenergic receptors). Beta blockers block the action of epinephrine in the body. Oral medication A medication is a licenced drug taken to cure or reduce symptoms of an illness or medical condition. ... Epinephrine (INN), also epinephrin (both pronounced ep-i-NEF-rin), or adrenaline (BAN) is a hormone and a neurotransmitter. ... In biochemistry, a receptor is a protein on the cell membrane or within the cytoplasm or cell nucleus that binds to a specific molecule (a ligand), such as a neurotransmitter, hormone, or other substance, and initiates the cellular response to the ligand. ... The adrenergic receptors (or adrenoceptors) are a class of G-protein coupled receptors that is the target of catecholamines. ... Beta blockers or beta-adrenergic blocking agents are a class of drugs used to treat a variety of cardiovascular conditions and some other diseases. ...

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Adrenergic Modulation of Erythropoiesis Following Trauma: The University Hospital, Newark, NJ (986 words)
Adrenergic modulation of erythropoiesis is known to occur under normal conditions and typically red blood cell growth is enhanced.
We hypothesize that since adrenergic stimulation occurs with trauma, the anemia associated with injury may be related to the cells’ altered ability to proliferate and differentiate into red blood cells.
Adrenergic agonists, epinephrine, norepinephrine and isoproterenol, were added to bone marrow cultures in vitro to assess their effect on erythropoietic progenitors, specifically erythroid burst forming units (BFU-E) and erythroid colony forming units (CFU-E).
Adrenergic Drugs (480 words)
Adrenergic drugs stimulate the adrenergic nerves directly by mimicking the action of norepinephrine.
Adrenergic stimulants may have three modes of action: direct interaction with specific receptors (examples are epinephrine and phenylephrine); indirect action by stimulating release of neurotransmitters; or a mixed action involving both of the above (examples are phenylpropanolamine and ephedrine).
When local anesthetics are used to reduce or eliminate pain in a specific area, epinephrine is frequently used in conjunction with these agents to constrict the blood vessels at the area and prevent drug diffusion from that area.
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