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Encyclopedia > Adhesin

Adhesin

Adhesins are antigens that may exist on the surface of microbes. Adhesins permit the microbe to cause binding of other cells or substances to the microbe.


  Results from FactBites:
 
Capsular polysaccharide adhesin antigen, preparation, purification and use - Patent 6399066 (6228 words)
Such adhesin antibodies are useful in vivo to prevent infection by nosocomial coagulase-negative staphylococcal strains, in assays for the detection of such bacteria, in assays for the estimation of such adhesins in complex mixtures, and as an affinity chromatography matrix.
In another preferred embodiment, the substantially pure polysaccharide adhesin of the invention is used as a vaccine to raise in animals antibodies against said adhesin that inhibit the attachment of adhesin-bearing bacteria to polymeric materials.
Briefly, the purified adhesin is used to once-prime or hyperimmunize animal donors of antibody-producing somatic B cells (e.g., lymphocytes).
Adhesin - Wikipedia, the free encyclopedia (187 words)
Adhesins are attractive vaccine candidates because they are often essential to infection and are surface-located, making them readily accessible to antibodies.
The effectiveness of anti-adhesin antibodies is illustrated by studies with FimH, the adhesin of uropathogenic Escherichia coli (UPEC).
Role of Adhesin Release for Mucosal Colonization by a Bacterial Pathogen
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