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Encyclopedia > Adenomatosis
Adenoma
ICD-10 D12, D350, D34, D352, and others
ICD-9 211.3, 211.5,223.0, 226, 227.0,
ICD-O: M8140/0

Adenoma refers to a collection of growths (-oma) of glandular origin. Adenomas can grow from many organs including the colon, adrenal, pituitary, thyroid, etc. These growths are benign, but some are known to have the potential, over time, to transform to malignancy (at which point they become known as adenocarcinoma.) The following codes are used with International Statistical Classification of Diseases and Related Health Problems. ... // C00-D48 - Neoplasms (C00-C14) Malignant neoplasms, lip, oral cavity and pharynx (C00) Malignant neoplasm of lip (C01) Malignant neoplasm of base of tongue (C02) Malignant neoplasm of other and unspecified parts of tongue (C03) Malignant neoplasm of gum (C04) Malignant neoplasm of floor of mouth (C05) Malignant neoplasm of... // C00-D48 - Neoplasms (C00-C14) Malignant neoplasms, lip, oral cavity and pharynx (C00) Malignant neoplasm of lip (C01) Malignant neoplasm of base of tongue (C02) Malignant neoplasm of other and unspecified parts of tongue (C03) Malignant neoplasm of gum (C04) Malignant neoplasm of floor of mouth (C05) Malignant neoplasm of... // C00-D48 - Neoplasms (C00-C14) Malignant neoplasms, lip, oral cavity and pharynx (C00) Malignant neoplasm of lip (C01) Malignant neoplasm of base of tongue (C02) Malignant neoplasm of other and unspecified parts of tongue (C03) Malignant neoplasm of gum (C04) Malignant neoplasm of floor of mouth (C05) Malignant neoplasm of... // C00-D48 - Neoplasms (C00-C14) Malignant neoplasms, lip, oral cavity and pharynx (C00) Malignant neoplasm of lip (C01) Malignant neoplasm of base of tongue (C02) Malignant neoplasm of other and unspecified parts of tongue (C03) Malignant neoplasm of gum (C04) Malignant neoplasm of floor of mouth (C05) Malignant neoplasm of... The following is a list of codes for International Statistical Classification of Diseases and Related Health Problems. ... The International Classification of Diseases for Oncology (ICD-O) is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems for tumor diseases. ... The International Classification of Diseases for Oncology (ICD-O) is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems for tumor diseases. ... Grays Fig. ... In mammals, the adrenal glands are the triangle-shaped endocrine glands that sit atop the kidneys. ... Located at the base of the skull, the pituitary gland is protected by a bony structure called the sella turcica. ... When normal cells are damaged or old they undergo apoptosis; cancer cells, however, avoid apoptosis. ... In medicine, carcinoma is any cancer that arises from epithelial cells. ...

Contents


Histopathology

Adenoma is a benign epithelial tumor arising in epithelium of mucosa (stomach, small intestine and bowel), glands (endocrine and exocrine) and ducts. The mucous membranes (or mucosa) are linings of ectodermic origin, covered in epithelium, that line various body cavities and internal organs. ...


In hollow organs (digestive tract) the adenoma grows upwards into the lumen - adenomatous polyp or polypoid adenoma. Polyp of sigmoid colon as revealed by colonoscopy. ...


Depending on the type of the insertion base, adenoma may be pedunculated (lobular head with a long, slender stalk, covered by normal mucosa) or sessile (broad base). The term lobe generally refers to a projecting part of an object, but it can have more specific meanings. ... This page is a candidate to be moved to Wiktionary. ...


The adenomatous proliferation is characterized by different degrees of cell dysplasia (atypia or loss of normal differentiation of epithelium): irregular cells with hyperchromatic nuclei, (pseudo)stratified nuclei, nucleolus, decreased mucosecretion and mitosis. Dysplasia is a situation where cells have changed from their original mature differentiated type into another mature differentiated cell type as an adaptive response to exposure to chronic irritation, or to a pathogen or carcinogen. ... In cell biology, the nucleolus is, strictly speaking, a suborganelle of the nucleus, which is an organelle. ... Light micrograph of a newt kidney cell in early anaphase of mitosis. ...


The architecture may be tubular, villous or tubulo-villous. Basement membrane and muscularis mucosae are intact. Tubular may refer to: the form of a cylinder (geometry) or tube tubular bell parts of the kidney distal convoluted tubule uriniferous tubule 80s Surfer talk for Badical This is a disambiguation page: a list of articles associated with the same title. ... ...


Locations

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Colonic adenoma

Colon (D12)

Adenomas of the colon are quite prevalent. They are found commonly at colonoscopy. They are removed because of their tendency to become malignant and lead to colon cancer. // C00-D48 - Neoplasms (C00-C14) Malignant neoplasms, lip, oral cavity and pharynx (C00) Malignant neoplasm of lip (C01) Malignant neoplasm of base of tongue (C02) Malignant neoplasm of other and unspecified parts of tongue (C03) Malignant neoplasm of gum (C04) Malignant neoplasm of floor of mouth (C05) Malignant neoplasm of... Colonoscopy is the minimally invasive endoscopic examination of the large colon and the distal part of the small bowel with a fiber optic camera on a flexible tube passed through the anus. ... Diagram of the stomach, colon, and rectum Colorectal cancer includes cancerous growths in the colon, rectum and appendix. ...


Adrenal (D350)

It has been suggested that Adrenal adenoma be merged into this article or section. (Discuss)

Adrenal adenomas are common (1 in 10 people have them), benign and asymptomatic. They are often found on CAT scans of the abdomen, usually not as the focus of investigation; they are usually incidental findings (incidentalomas). About one in 10,000 is malignant. Thus, a biopsy is rarely called for, especially if the lesion is homogeneous and smaller than 3 centrimeters. Follow-up images in three to six months can confirm the stability of the growth. // C00-D48 - Neoplasms (C00-C14) Malignant neoplasms, lip, oral cavity and pharynx (C00) Malignant neoplasm of lip (C01) Malignant neoplasm of base of tongue (C02) Malignant neoplasm of other and unspecified parts of tongue (C03) Malignant neoplasm of gum (C04) Malignant neoplasm of floor of mouth (C05) Malignant neoplasm of... Image File history File links Please see the file description page for further information. ... CAT apparatus in a hospital Computed axial tomography (CAT), computer-assisted tomography, computed tomography, CT, or body section roentgenography is the process of using digital processing to generate a three-dimensional image of the internals of an object from a large series of two-dimensional X-ray images taken around... The abdomen is a part of the body. ... In medicine, an incidentaloma is a tumor (-oma) found by coincidence (incidental) without clinical symptoms and suspicion. ...


Malignant growth of the adrenal is called adrenal adenocarcinoma.


In patients with symptoms of Cushing's syndrome, adrenal adenomas are frequently the focus of glucocorticoid secretion. Surgical resection may be indicated; those unfit for surgery benefit from suppression of the cortisol production with ketoconazole or metyrapone. Glucocorticoids are a class of steroid hormones characterised by an ability to bind with the cortisol receptor and trigger similar effects. ... Ketoconazole Ketoconazole is a synthetic antifungal drug used to prevent and treat skin and fungal infections, especially in immunocompromised patients such as those with AIDS. Due to its side-effect profile, it has been superseded by newer antifungals, such as fluconazole and itraconazole. ... Metyrapone (Metopirone™) is a drug used in the diagnosis, and occasionally the treatment, of Cushings syndrome (hypercortisolism). ...


Thyroid (D34)

About one in 10 people are found to have solitary thyroid nodules. Investigation is required because a small percentage of these are malignant. Biopsy usually confirms the growth to be an adenoma, but sometimes, excision at surgery is required, especially when the cells found at biopsy are of the follicular type. // C00-D48 - Neoplasms (C00-C14) Malignant neoplasms, lip, oral cavity and pharynx (C00) Malignant neoplasm of lip (C01) Malignant neoplasm of base of tongue (C02) Malignant neoplasm of other and unspecified parts of tongue (C03) Malignant neoplasm of gum (C04) Malignant neoplasm of floor of mouth (C05) Malignant neoplasm of... // Solitary Thyroid Nodule Risks for Cancer Solitary thyroid nodules are worrisome in patients who have had prior radiation to the head and neck, and in those who have a family history of thyroid cancer. ... A biopsy (in Greek: bios = life and opsy = look/appearance) is a medical test involving the removal of cells or tissues for examination. ... A typical modern surgical operation For other uses, see Surgery (disambiguation). ...


Pituitary (D352)

Pituitary adenomas are commonly seen in 10% of the neurological patients. A lot of them remain undiagnosed. Treatment is usually surgical, to which patients generally respond well. The most common subtype, prolactinoma, is seen more often in women, and is frequently diagnosed during pregnancy as the hormone progesterone increases its growth. Medical therapy (bromocriptine) generally suppresses prolactinomas; progesterone antagonist therapy has not proven to be successful. // C00-D48 - Neoplasms (C00-C14) Malignant neoplasms, lip, oral cavity and pharynx (C00) Malignant neoplasm of lip (C01) Malignant neoplasm of base of tongue (C02) Malignant neoplasm of other and unspecified parts of tongue (C03) Malignant neoplasm of gum (C04) Malignant neoplasm of floor of mouth (C05) Malignant neoplasm of... Pituitary adenomas are tumors that occur in the pituitary gland, and account for about 10% of intracranial neoplasms. ... A prolactinoma is a benign tumor (adenoma) of the pituitary gland that produces a hormone called prolactin. ... Bromocriptine is an ergoline derivative dopamine agonist that is used in the treatment of pituitary tumors and Parkinsons disease. ...


Liver

Hepatic adenomas are a rare benign tumour of the liver (hepatic tumour), which may present with hepatomegaly or other symptoms. The liver is the largest internal organ in the human body. ... Hepatomegaly is an enlargement of the liver (swelling). ...


External links

Photos at: Atlas of Pathology

Tumors (and related structures), Cancer, and Oncology
Benign - Premalignant - Carcinoma in situ - Malignant

Topography: Anus - Bladder - Bone - Brain - Breast - Cervix - Colon/rectum - Duodenum - Endometrium - Esophagus - Eye - Gallbladder - Head/Neck - Liver - Larynx - Lung - Mouth - Pancreas - Penis - Prostate - Kidney - Ovaries - Skin - Stomach - Testicles - Thyroid Tumor (American English) or tumour (British English) originally means swelling, and is sometimes still used with that meaning. ... When normal cells are damaged beyond repair, they are eliminated by apoptosis. ... Oncology is the medical subspecialty dealing with the study and treatment of cancer. ... Benign can refer to any medical condition which, untreated or with symptomatic therapy, will not become life-threatening. ... A premalignant condition is a disease, syndrome, or finding that, if left untreated, may lead to cancer. ... Carcinoma in situ is present when a tumor has been detected that has the characteristics of malignancy but has not invaded other tissues. ... In medicine, malignant is a clinical term that is used to describe a clinical course that progresses rapidly to death. ... Anal cancer is a distinct entity from the more common colorectal cancer. ... Cystoscopic view of a papillary bladder tumor (top); the bladder wall is visible on the bottom right Bladder cancer refers to any of several types of malignant growths of the urinary bladder. ... Bone tumor is an inexact term, which can be used for both benign and malignant abnormal growths found in bone, but is most commonly used for primary tumors of bone, such as osteosarcoma (or osteoma). ... A brain tumor is any intracranial mass created by an abnormal and uncontrolled growth of cells either normally found in the brain itself: neurons, glial cells (astrocytes, oligodendrocytes, ependymal cells), lymphatic tissue, blood vessels), in the cranial nerves (myelin producing Schwann cells), in the brain envelopes (meninges), skull, pituitary and... Breast cancer is cancer of breast tissue. ... Cervical cancer is a malignancy of the cervix. ... Colorectal cancer, also called colon cancer or bowel cancer, includes cancerous growths in the colon, rectum and appendix. ... This article needs more context around or a better explanation of technical details to make it more accessible to general readers and technical readers outside the specialty, without removing technical details. ... Endometrial cancer involves cancerous growth of the endometrium (lining of the uterus). ... Esophageal cancer is malignancy of the esophagus. ... Cancers can affect the eye. ... Bold textA more uncommon cancer predominate in females, if found early on before symptoms, can be cured by removing Gallbladder, most often it is found after symptoms occur (abdominal pain, Jaundice) and has spread to other organs such as liver and the outlook at this point is poor. ... Head and neck cancers are malignant growths located in the oral cavity (mouth), nasal cavity, pharynx, larynx, thyroid, paranasal sinuses, salivary glands and lymph nodes of the upper neck. ... Hepatocellular carcinoma (HCC, also called hepatoma or liver cancer) is a primary malignancy (cancer) of the liver. ... Cancer of the larynx also may be called laryngeal cancer. ... Lung cancer is a cancer of the lungs characterized by the presence of malignant tumors. ... Oral cancer is any cancerous tissue growth located in the mouth. ... Pancreatic cancer (also called cancer of the pancreas) is represented by the growth of a malignant tumour within the small pancreas organ. ... Penile cancer is a malignant growth found on the skin or in the tissues of the penis, usually originating in the glans and/or foreskin. ... Å…ÄŸ Prostate cancer is a disease in which cancer develops in the prostate, a gland in the male reproductive system. ... Renal cell carcinoma, also known by the eponym Grawitz tumor, is the most common form of kidney cancer arising from the renal tubule. ... Ovarian cancer is a malignant ovarian neoplasm (an abnormal growth located on the ovaries). ... In medicine (dermatology), there are several different types of cancer referred to under the general label of skin cancer. ... To meet Wikipedias quality standards, this article or section may require cleanup. ... Testicular cancer is a type of cancer that develops in the testicles, a part of the male reproductive system. ...


Morphology: Papilloma/carcinoma - Adenoma/adenocarcinoma - Soft tissue sarcoma - Melanoma - Fibroma/fibrosarcoma - Lipoma/liposarcoma - Leiomyoma/leiomyosarcoma - Rhabdomyoma/rhabdomyosarcoma - Mesothelioma - Angioma/angiosarcoma - Osteoma/osteosarcoma - Chondroma/chondrosarcoma - Glioma - Lymphoma/leukemia Human papillomavirus (HPV) is a virus which affects humans. ... In medicine, carcinoma is any cancer that arises from epithelial cells. ... In medicine, carcinoma is any cancer that arises from epithelial cells. ... Malignant (cancerous) tumors that develop in soft tissue are called sarcomas, a term that comes from a Greek word meaning fleshy growth. ... Skin cancer, close-up of level IV melanoma Melanoma is a malignant tumour of melanocytes . ... Fibroma. ... Fibrosarcoma (fibroblastic sarcoma) is a malignant tumor derived from fibrous connective tissue and characterized by immature proliferating fibroblasts or undifferentiated anaplastic spindle cells. ... A lipoma is a common, benign tumor composed of fatty tissue. ... This article needs to be cleaned up to conform to a higher standard of quality. ... A leiomyoma (plural is leiomyomata) is a benign smooth muscle neoplasm that is not premalignant. ... A sarcoma is a cancer of the bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. ... A rhabdomyoma is a benign tumor of muscle. ... A rhabdomyosarcoma is a type of cancer, specifically a sarcoma (cancer of connective tissues), in which the cancer cells arise from skeletal muscle. ... Angiomas are benign tumors that are made up of small blood vessels. ... Angiosarcoma is a rare, malignant tumor consisting of endothelial and fibroblastic tissue that proliferates and eventually surrounds vascular channels. ... An osteoma is a new piece of bone growing on another piece, typically the skull. ... Osteosarcoma is a common primary bone cancer. ... A chondroma is a benign cartilaginous tumor, which is encapsulated with a lobular growing pattern. ... A chondrosarcoma is a cancer of the cartilage. ... A glioma is a type of primary central nervous system (CNS) tumor that arises from glial cells. ... Lymphoma is a variety of cancer that originates in the lymphatic system. ... Leukemia or leukaemia (see spelling differences) is a cancer of the blood or bone marrow characterized by an abnormal proliferation of blood cells, usually white blood cells (leukocytes). ...


Treatment: Chemotherapy - Radiation therapy - Immunotherapy - Experimental cancer treatment Chemotherapy is the use of chemical substances to treat disease. ... Clinac 2100 C accelerator Radiation therapy (or radiotherapy) is the medical use of ionising radiation as part of cancer treatment to control malignant cells (not to be confused with radiology, the use of radiation in medical imaging and diagnosis). ... Cancer Immunotherapy is the use of the immune system to reject cancer. ... Experimental cancer treatments are medical therapies intended or claimed to treat cancer (see also tumor) by improving on, supplementing or replacing conventional methods (surgery, chemotherapy, radiation, and immunotherapy). ...


Related structures: Cyst - Dysplasia - Hamartoma - Neoplasia - Nodule - Polyp - Pseudocyst This is an article about cysts in the body. ... Dysplasia is a situation where cells have changed from their original mature differentiated type into another mature differentiated cell type as an adaptive response to exposure to chronic irritation, or to a pathogen or carcinogen. ... A hamartoma is an abnormal growth of normal cells. ... Neoplasia (literally: new growth) is abnormal, disorganized growth in a tissue or organ, usually forming a distinct mass. ... In medicine, a nodule refers to a small aggregation of cells. ... Polyp of sigmoid colon as revealed by colonoscopy. ... A pseudocyst is a pathological collection of fluid. ...


Misc: Tumor suppressor genes/oncogenes - Staging/grading - Carcinogenesis/metastasis - Carcinogen - Research - Paraneoplastic phenomenon - ICD-O - List of oncology-related terms A tumor suppressor gene is a gene that reduces the probability that a cell in a multicellular organism will turn into a tumor cell. ... An oncogene is a modified gene that increases the malignancy of a tumor cell. ... The stage of a cancer is a descriptor (usually numbers I to IV) of how much the cancer has spread. ... In pathology, Grading is a measure of the progress of tumors. ... Cancers are caused by a series of mutations. ... Metastasis (Greek: change of the state) is the spread of cancer from its primary site to other places in the body. ... // Carcinogen In pathology, a carcinogen is any substance or agent that promotes cancer. ... Cancer research is the intense scientific effort to understand the development of cancer and identify potential therapies. ... A paraneoplastic phenomenon is a disease or symptom that is the consequence of the presence of cancer in the body, but is not due to the local presence of cancer cells. ... The International Classification of Diseases for Oncology (ICD-O) is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems for tumor diseases. ... This is a list of terms related to oncology. ...


 
 

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