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Encyclopedia > Acute phase response

Acute phase proteins are a class of proteins that are synthetized in the liver in response to inflammation. This response is called the acute phase reaction.


In response to injury, local inflammatory cells (neutrophil granulocytes and macrophages) secrete a number of cytokines into the bloodstream, most notably the interleukins IL-1, IL-6 and IL-11 and TNF_alpha.


The liver responds by producing a large number of acute phase reactants, most notably:



  Results from FactBites:
 
Acute phase protein - Wikipedia, the free encyclopedia (132 words)
Acute phase proteins are a class of proteins that are synthetized in the liver in response to inflammation.
In response to injury, local inflammatory cells (neutrophil granulocytes and macrophages) secrete a number of cytokines into the bloodstream, most notably the interleukins IL-1, IL-6 and IL-8 and TNF-alpha.
Measurement of acute phase proteins is a useful marker of inflammation in both medical and veterinary clinical pathology.
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