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Encyclopedia > Acetyl

Acetyl is the radical of acetic acid. It contains a methyl group single-bonded to a carbonyl. The carbon of the carbonyl has an lone electron available, with which it forms a chemical bond to the remainder of the molecule. The chemical structure is

 O=C- | CH3 

The acetyl radical is a component of many organic compounds, including acetyl-CoA, the neurotransmitter acetylcholine, and the analgesics acetaminophen and acetylsalicylic acid (better known as aspirin).

  Results from FactBites:
Reference.com/Encyclopedia/Acetyl-CoA (551 words)
Its main use is to convey the carbon atoms within the acetyl group to Krebs Cycle to be oxidized for energy production.
Chemically it is the thioester between coenzyme A (a thiol) and acetic acid (an acyl group carrier).
Furthermore, it contributes an acetyl group to choline to produce acetylcholine, in a reaction catalysed by choline acetyltransferase.
Acetyl l Carnitine by Ray Sahelian, MD, benefit of acetyl l carnitine benefit (5003 words)
The acetyl group of acetyl l carnitine is used to form acetyl-CoA, the most important intermediary in the generation of energy from amino acids, fats, and carbohydrates.
In conclusion, acetyl L carnitine and L-carnitine were similar in increasing ambulatory activity in old rats and elevating carnitine levels in blood and brain.
To compare the efficacy of Acetyl carnitine with that of amantadine, one of the drugs most widely used to treat MS-related fatigue, 36 MS patients presenting fatigue were enrolled in a randomised, double-blind, crossover study.
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